Human SH2B3/IDDM20/ LNK ORF/cDNA clone-Lentivirus particle (NM_005475.2)
Pre-made Human SH2B3/IDDM20/ LNK Lentiviral expression plasmid for SH2B3 lentivirus packaging, SH2B3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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Product information
Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLV000209 | Human SH2B3 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLV000209 |
Gene Name | SH2B3 |
Accession Number | NM_005475.2 |
Gene ID | 10019 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 1728 bp |
Gene Alias | IDDM20, LNK |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocinmyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T44585-Ab | Anti-SH2B3 monoclonal antibody |
Target Antigen | GM-Tg-g-T44585-Ag | SH2B3 protein |
ORF Viral Vector | pGMLV000209 | Human SH2B3 Lentivirus plasmid |
ORF Viral Vector | vGMLV000209 | Human SH2B3 Lentivirus particle |
Target information
Target ID | GM-T44585 |
Target Name | SH2B3 |
Gene ID | 10019, 16923, 710839, 58838, 101081760, 100683018, 614726, 100057885 |
Gene Symbol and Synonyms | IDDM20,LNK,SH2B3 |
Uniprot Accession | Q9UQQ2 |
Uniprot Entry Name | SH2B3_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000111252 |
Target Classification | Not Available |
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.