Human RASGRP1/CALDAG-GEFI/ CALDAG-GEFII ORF/cDNA clone-Lentivirus particle (NM_005739)
Pre-made Human RASGRP1/CALDAG-GEFI/ CALDAG-GEFII Lentiviral expression plasmid for RASGRP1 lentivirus packaging, RASGRP1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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Product information
Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLV000208 | Human RASGRP1 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLV000208 |
Gene Name | RASGRP1 |
Accession Number | NM_005739 |
Gene ID | 10125 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 2394 bp |
Gene Alias | CALDAG-GEFI, CALDAG-GEFII, IMD64, RASGRP |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocinmyocin |
Fusion Tag | Null |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-MP2286-Ab | Anti-GRP1/ RASGRP1/ CALDAG-GEFI monoclonal antibody |
Target Antigen | GM-Tg-g-MP2286-Ag | RASGRP1 VLP (virus-like particle) |
ORF Viral Vector | pGMLV000208 | Human RASGRP1 Lentivirus plasmid |
ORF Viral Vector | pGMPC000881 | Human RASGRP1 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMLV000208 | Human RASGRP1 Lentivirus particle |
Target information
Target ID | GM-MP2286 |
Target Name | RASGRP1 |
Gene ID | 10125, 19419, 703838, 29434, 101093110, 478255, 533125, 100071578 |
Gene Symbol and Synonyms | CALDAG-GEFI,CALDAG-GEFII,IMD64,RASGRP,RASGRP1 |
Uniprot Accession | O95267 |
Uniprot Entry Name | GRP1_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Not Available |
Disease | Not Available |
Gene Ensembl | ENSG00000172575 |
Target Classification | Not Available |
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.