Human PPIB/CYP-S1/CYPB ORF/cDNA clone-Lentivirus particle (NM_000942)
Cat. No.: vGMLP002164
Pre-made Human PPIB/CYP-S1/CYPB Lentiviral expression plasmid for PPIB lentivirus packaging, PPIB lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP002164 | Human PPIB Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP002164 |
Gene Name | PPIB |
Accession Number | NM_000942 |
Gene ID | 5479 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 651 bp |
Gene Alias | CYP-S1,CYPB,HEL-S-39,OI9,SCYLP |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGCTGCGCCTCTCCGAACGCAACATGAAGGTGCTCCTTGCCGCCGCCCTCATCGCGGGGTCCGTCTTCTTCCTGCTGCTGCCGGGACCTTCTGCGGCCGATGAGAAGAAGAAGGGGCCCAAAGTCACCGTCAAGGTGTATTTTGACCTACGAATTGGAGATGAAGATGTAGGCCGGGTGATCTTTGGTCTCTTCGGAAAGACTGTTCCAAAAACAGTGGATAATTTTGTGGCCTTAGCTACAGGAGAGAAAGGATTTGGCTACAAAAACAGCAAATTCCATCGTGTAATCAAGGACTTCATGATCCAGGGCGGAGACTTCACCAGGGGAGATGGCACAGGAGGAAAGAGCATCTACGGTGAGCGCTTCCCCGATGAGAACTTCAAACTGAAGCACTACGGGCCTGGCTGGGTGAGCATGGCCAACGCAGGCAAAGACACCAACGGCTCCCAGTTCTTCATCACGACAGTCAAGACAGCCTGGCTAGATGGCAAGCATGTGGTGTTTGGCAAAGTTCTAGAGGGCATGGAGGTGGTGCGGAAGGTGGAGAGCACCAAGACAGACAGCCGGGATAAACCCCTGAAGGATGTGATCATCGCAGACTGCGGCAAGATCGAGGTGGAGAAGCCCTTTGCCATCGCCAAGGAGTAG |
ORF Protein Sequence | MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T25847-Ab | Anti-PPIB/ B/ CYP-S1 functional antibody |
Target Antigen | GM-Tg-g-T25847-Ag | PPIB protein |
ORF Viral Vector | pGMLP002164 | Human PPIB Lentivirus plasmid |
ORF Viral Vector | pGMPC001690 | Human PPIB Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMLP002164 | Human PPIB Lentivirus particle |
Target information
Target ID | GM-T25847 |
Target Name | PPIB |
Gene ID | 5479, 19035, 706757, 64367, 101087581, 478337, 281419, 100066834 |
Gene Symbol and Synonyms | Cphn-2,Cphn2,CyP-20b,CYP-S1,CYPB,HEL-S-39,OI9,PPIB,SCYLP |
Uniprot Accession | P23284 |
Uniprot Entry Name | PPIB_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000166794 |
Target Classification | Not Available |
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
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