Human ERLIN2/C8orf2/Erlin-2 ORF/cDNA clone-Lentivirus particle (NM_007175)

Cat. No.: vGMLP001235

Pre-made Human ERLIN2/C8orf2/Erlin-2 Lentiviral expression plasmid for ERLIN2 lentivirus packaging, ERLIN2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP001235 Human ERLIN2 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP001235
Gene Name ERLIN2
Accession Number NM_007175
Gene ID 11160
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 1020 bp
Gene Alias C8orf2,Erlin-2,NET32,SPFH2,SPG18
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCTCAGTTGGGAGCAGTTGTGGCTGTGGCTTCCAGTTTCTTTTGTGCATCTCTCTTCTCAGCTGTGCACAAGATAGAAGAGGGACATATTGGGGTATATTACAGAGGCGGTGCCCTGCTGACTTCGACCAGCGGCCCTGGTTTCCATCTCATGCTCCCTTTCATCACATCATATAAGTCTGTGCAGACCACACTCCAGACAGATGAGGTGAAGAATGTACCTTGTGGGACTAGTGGTGGTGTGATGATCTACTTTGACAGAATTGAAGTGGTGAACTTCCTGGTCCCGAACGCAGTGTATGATATAGTGAAGAACTATACTGCTGACTATGACAAGGCCCTCATCTTCAACAAGATCCACCACGAACTGAACCAGTTCTGCAGTGTGCACACGCTTCAAGAGGTCTACATTGAGCTGTTTGATCAGATTGATGAAAATCTCAAACTGGCTTTGCAACAGGACCTGACCTCCATGGCCCCTGGGCTGGTCATTCAAGCTGTGCGGGTAACAAAGCCCAACATACCAGAGGCAATCCGCAGAAACTACGAGTTGATGGAAAGTGAGAAGACAAAGCTTCTCATTGCCGCCCAGAAACAGAAGGTGGTGGAAAAGGAAGCAGAGACAGAGCGGAAGAAGGCGCTCATTGAGGCAGAAAAAGTGGCCCAGGTGGCTGAGATCACCTACGGGCAGAAGGTGATGGAGAAGGAGACTGAGAAGAAGATTTCAGAAATTGAAGATGCTGCATTTCTGGCCCGGGAGAAGGCAAAGGCAGATGCTGAGTGCTACACTGCTATGAAAATAGCCGAAGCCAATAAGCTGAAGCTAACCCCTGAATATCTGCAGCTGATGAAGTACAAGGCCATTGCTTCCAACAGCAAGATTTACTTTGGCAAAGACATTCCTAACATGTTCATGGACTCTGCGGGCAGTGTGAGCAAGCAGTTTGAGGGGCTAGCTGACAAGCTAAGCTTTGGCTTAGAAGATGAACCCTTGGAGACGGCCACTAAGGAGAATTGA
ORF Protein Sequence MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGSVSKQFEGLADKLSFGLEDEPLETATKEN

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2591-Ab Anti-ERLN2/ ERLIN2/ C8orf2 monoclonal antibody
    Target Antigen GM-Tg-g-MP2591-Ag ERLIN2 VLP (virus-like particle)
    ORF Viral Vector pGMLP001235 Human ERLIN2 Lentivirus plasmid
    ORF Viral Vector vGMLP001235 Human ERLIN2 Lentivirus particle


    Target information

    Target ID GM-MP2591
    Target Name ERLIN2
    Gene ID 11160, 244373, 698126, 290823, 101089349, 607518, 616278, 100057973
    Gene Symbol and Synonyms C8orf2,Erlin-2,ERLIN2,NET32,RGD1309010,SPFH2,SPG18
    Uniprot Accession O94905
    Uniprot Entry Name ERLN2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000147475
    Target Classification Not Available

    This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]



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