Human PLA2G10/GXPLA2/GXSPLA2 ORF/cDNA clone-Lentivirus particle (NM_003561)
Cat. No.: vGMLP000902
Pre-made Human PLA2G10/GXPLA2/GXSPLA2 Lentiviral expression plasmid for PLA2G10 lentivirus packaging, PLA2G10 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP000902 | Human PLA2G10 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP000902 |
Gene Name | PLA2G10 |
Accession Number | NM_003561 |
Gene ID | 8399 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 498 bp |
Gene Alias | GXPLA2,GXSPLA2,SPLA2,sPLA2-X |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGGGGCCGCTACCTGTGTGCCTGCCAATCATGCTGCTCCTGCTACTGCCGTCGCTGCTGCTGCTGCTGCTTCTACCTGGCCCCGGGTCCGGCGAGGCCTCCAGGATATTACGTGTGCACCGGCGTGGGATCCTGGAACTGGCAGGAACTGTGGGTTGTGTTGGTCCCCGAACCCCCATCGCCTATATGAAATATGGTTGCTTTTGTGGCTTGGGAGGCCATGGCCAGCCCCGCGATGCCATTGACTGGTGCTGCCATGGCCACGACTGTTGTTACACTCGAGCTGAGGAGGCCGGCTGCAGCCCCAAGACAGAGCGCTACTCCTGGCAGTGCGTCAATCAGAGCGTCCTGTGCGGACCGGCAGAGAACAAATGCCAAGAACTGTTGTGCAAGTGTGACCAGGAGATTGCTAACTGCTTAGCCCAAACTGAGTACAACTTAAAGTACCTCTTCTACCCCCAGTTCCTATGTGAGCCGGACTCGCCCAAGTGTGACTGA |
ORF Protein Sequence | MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-SE0409-Ab | Anti-PA2GX/ PLA2G10/ GXPLA2 functional antibody |
Target Antigen | GM-Tg-g-SE0409-Ag | PLA2G10 protein |
ORF Viral Vector | pGMLP000902 | Human PLA2G10 Lentivirus plasmid |
ORF Viral Vector | vGMLP000902 | Human PLA2G10 Lentivirus particle |
Target information
Target ID | GM-SE0409 |
Target Name | PLA2G10 |
Gene ID | 8399, 26565, 29359, 100054324 |
Gene Symbol and Synonyms | GX sPLA2,GXPLA2,GXSPLA2,PLA2G10,PLA2GX,SPLA2,sPLA2-X |
Uniprot Accession | O15496 |
Uniprot Entry Name | PA2GX_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Not Available |
Disease | Not Available |
Gene Ensembl | ENSG00000069764 |
Target Classification | Not Available |
This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]
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