Human SMAD3/DKFZP586N0721/HSPC193 ORF/cDNA clone-Lentivirus particle (BC050743)
Cat. No.: vGMLP000019
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human SMAD3/DKFZP586N0721/HSPC193 Lentiviral expression plasmid for SMAD3 lentivirus packaging, SMAD3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP000019 | Human SMAD3 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP000019 |
Gene Name | SMAD3 |
Accession Number | BC050743 |
Gene ID | 4088 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 1278 bp |
Gene Alias | DKFZP586N0721,HSPC193,HsT17436,JV15-2,MGC60396,Smad 3 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Sequence | ATGTCGTCCATCCTGCCTTTCACTCCCCCGATCGTGAAGCGCCTGCTGGGCTGGAAGAAGGGCGAGCAGAACGGGCAGGAGGAGAAATGGTGCGAGAAGGCGGTCAAGAGCCTGGTCAAGAAACTCAAGAAGACGGGGCAGCTGGACGAGCTGGAGAAGGCCATCACCACGCAGAACGTCAACACCAAGTGCATCACCATCCCCAGGTCCCTGGATGGCCGGTTGCAGGTGTCCCATCGGAAGGGGCTCCCTCATGTCATCTACTGCCGCCTGTGGCGATGGCCAGACCTGCACAGCCACCACGAGCTGCGGGCCATGGAGCTGTGTGAGTTCGCCTTCAATATGAAGAAGGACGAGGTCTGCGTGAATCCCTACCACTACCAGAGAGTAGAGACACCAGTTCTACCTCCTGTGTTGGTGCCACGCCACACAGAGATCCCGGCCGAGTTCCCCCCACTGGACGACTACAGCCATTCCATCCCCGAAAACACTAACTTCCCCGCAGGCATCGAGCCCCAGAGCAATATTCCAGAGACCCCACCCCCTGGCTACCTGAGTGAAGATGGAGAAACCAGTGACCACCAGATGAACCACAGCATGGACGCAGGTTCTCCAAACCTATCCCCGAATCCGATGTCCCCAGCACATAATAACTTGGACCTGCAGCCAGTTACCTACTGCGAGCCGGCCTTCTGGTGCTCCATCTCCTACTACGAGCTGAACCAGCGCGTCGGGGAGACATTCCACGCCTCGCAGCCATCCATGACTGTGGATGGCTTCACCGACCCCTCCAATTCGGAGCGCTTCTGCCTAGGGCTGCTCTCCAATGTCAACAGGAATGCAGCAGTGGAGCTGACACGGAGACACATCGGAAGAGGCGTGCGGCTCTACTACATCGGAGGGGAGGTCTTCGCAGAGTGCCTCAGTGACAGCGCTATTTTTGTCCAGTCTCCCAACTGTAACCAGCGCTATGGCTGGCACCCGGCCACCGTCTGCAAGATCCCACCAGGATGCAACCTGAAGATCTTCAACAACCAGGAGTTCGCTGCCCTCCTGGCCCAGTCGGTCAACCAGGGCTTTGAGGCTGTCTACCAGTTGACCCGAATGTGCACCATCCGCATGAGCTTCGTCAAAGGCTGGGGAGCGGAGTACAGGAGACAGACTGTGACCAGTACCCCCTGCTGGATTGAGCTGCACCTGAATGGGCCTTTGCAGTGGCTTGACAAGGTCCTCACCCAGATGGGCTCCCCAAGCATCCGCTGTTCCAGTGTGTCTTAG |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T35445-Ab | Anti-SMAD3 monoclonal antibody |
Target Antigen | GM-Tg-g-T35445-Ag | SMAD3 protein |
Cytokine | cks-Tg-g-GM-T35445 | SMAD family member 3 (SMAD3) protein & antibody |
ORF Viral Vector | pGMLP000019 | Human SMAD3 Lentivirus plasmid |
ORF Viral Vector | pGMAP000252 | Human SMAD3 Adenovirus plasmid |
ORF Viral Vector | pGMLP-SPh-045 | Human SMAD3 Lentivirus plasmid |
ORF Viral Vector | pGMAP-SPh-185 | Human SMAD3 Adenovirus plasmid |
ORF Viral Vector | pGMPC000481 | Human SMAD3 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMLP000019 | Human SMAD3 Lentivirus particle |
ORF Viral Vector | vGMAP000252 | Human SMAD3 Adenovirus particle |
ORF Viral Vector | vGMLP-SPh-045 | Human SMAD3 Lentivirus particle |
ORF Viral Vector | vGMAP-SPh-185 | Human SMAD3 Adenovirus particle |
Target information
Target ID | GM-T35445 |
Target Name | SMAD3 |
Gene ID | 4088, 17127, 711355, 25631, 101101387, 610902, 515125, 100033845 |
Gene Symbol and Synonyms | hMAD-3,hSMAD3,HSPC193,HsT17436,JV15-2,LDS1C,LDS3,mad3,MADH3,Smad 3,SMAD3 |
Uniprot Accession | P84022 |
Uniprot Entry Name | SMAD3_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target, Cytokine Target |
Disease | Cancer |
Gene Ensembl | ENSG00000166949 |
Target Classification | Tumor-associated antigen (TAA) |
The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]
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