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Human SIGIRR/TIR8 ORF/cDNA clone-Adenovirus particle (BC003591)
Cat. No.: vGMAP000069
Pre-made Human SIGIRR/TIR8 Adenovirus for SIGIRR overexpression in-vitro and in-vivo. The SIGIRR adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified SIGIRR-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000069 | Human SIGIRR Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000069 |
| Gene Name | SIGIRR |
| Accession Number | BC003591 |
| Gene ID | 59307 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 1233 bp |
| Gene Alias | TIR8 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Kanamycin |
| ORF Nucleotide Sequence | ATGCCAGGTGTCTGTGATAGGGCCCCTGACTTCCTCTCCCCGTCTGAAGACCAGGTGCTGAGGCCTGCCTTGGGCAGCTCAGTGGCTCTGAACTGCACGGCTTGGGTAGTCTCTGGGCCCCACTGCTCCCTGCCTTCAGTCCAGTGGCTGAAAGACGGGCTTCCATTGGGAATTGGGGGCCACTACAGCCTCCACGAGTACTCCTGGGTCAAGGCCAACCTGTCAGAGGTGCTTGTGTCCAGTGTCCTGGGGGTCAACGTGACCAGCACTGAAGTCTATGGGGCCTTCACCTGCTCCATCCAGAACATCAGCTTCTCCTCCTTCACTCTTCAGAGAGCTGGCCCTACAAGCCACGTGGCTGCGGTGCTGGCCTCCCTCCTGGTCCTGCTGGCCCTGCTGCTGGCCGCCCTGCTCTATGTCAAGTGCCGTCTCAACGTGCTGCTCTGGTACCAGGACGCGTATGGGGAGGTGGAGATAAACGACGGGAAGCTCTACGACGCCTACGTCTCCTACAGCGACTGCCCCGAGGACCGCAAGTTCGTGAACTTCATCCTAAAGCCGCAGCTGGAGCGGCGTCGGGGCTACAAGCTCTTCCTGGACGACCGCGACCTCCTGCCGCGCGCTGAGCCCTCCGCCGACCTCTTGGTGAACCTGAGCCGCTGCCGACGCCTCATCGTGGTGCTTTCGGACGCCTTCCTGAGCCGGGCCTGGTGCAGCCACAGCTTCCGGGAGGGCCTGTGCCGGCTGCTGGAGCTCACCCGCAGACCCATCTTCATCACCTTCGAGGGCCAGAGGCGCGACCCCGCGCACCCGGCGCTCCGCCTGCTGCGCCAGCACCGCCACCTGGTGACCTTGCTGCTCTGGAGGCCCGGCTCCGTGACTCCTTCCTCCGATTTTTGGAAAGAAGTGCAGCTGGCGCTGCCGCGGAAGGTGCGGTACAGGCCGGTGGAAGGAGACCCCCAGACGCAGCTGCAGGACGACAAGGACCCCATGCTGATTCTTCGAGGCCGAGTCCCTGAGGGCCGGGCCCTGGACTCAGAGGTGGACCCGGACCCTGAGGGCGACCTGGGTGTCCGGGGGCCTGTTTTTGGAGAGCCATCAGCTCCACCGCACACCAGTGGGGTCTCGCTGGGAGAGAGCCGGAGCAGCGAAGTGGACGTCTCGGATCTCGGCTCGCGAAACTACAGTGCCCGCACAGACTTCTACTGCCTGGTGTCCAAGGATGATATGTAG |
| ORF Protein Sequence | MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVRYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-MP1516-Ab | Anti-SIGIR/ SIGIRR/ IL-1R8 monoclonal antibody |
| Target Antigen | GM-Tg-g-MP1516-Ag | SIGIRR VLP (virus-like particle) |
| Cytokine | cks-Tg-g-GM-MP1516 | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR) protein & antibody |
| ORF Viral Vector | pGMLV000704 | Human SIGIRR Lentivirus plasmid |
| ORF Viral Vector | pGMAP000069 | Human SIGIRR Adenovirus plasmid |
| ORF Viral Vector | vGMLV000704 | Human SIGIRR Lentivirus particle |
| ORF Viral Vector | vGMAP000069 | Human SIGIRR Adenovirus particle |
Target information
| Target ID | GM-MP1516 |
| Target Name | SIGIRR |
| Gene ID | 59307, 24058, 309106, 101100416, 100686933, 531801, 100054544 |
| Gene Symbol and Synonyms | IL-1R8,RGD1306732,SIGIRR,TIR8 |
| Uniprot Accession | Q6IA17 |
| Uniprot Entry Name | SIGIR_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | Not Available |
| Gene Ensembl | ENSG00000185187 |
| Target Classification | Not Available |
Predicted to enable NAD+ nucleosidase activity. Involved in negative regulation of DNA-binding transcription factor activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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