Human TGFBR3/betaglycan/BGCAN ORF/cDNA clone-Adenovirus particle (NM_003243)

SKU: vGMAP-SPh-182
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TGFBR3/betaglycan/BGCAN Adenovirus for TGFBR3 overexpression in-vitro and in-vivo. The TGFBR3 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified TGFBR3-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAP-SPh-182 Human TGFBR3 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAP-SPh-182
Gene Name TGFBR3
Accession Number NM_003243
Gene ID 7049
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 2556 bp
Gene Alias betaglycan,BGCAN
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0500-Ab Anti-TGBR3/ TGFBR3/ BGCAN functional antibody
    Target Antigen GM-Tg-g-SE0500-Ag TGFBR3 protein
    Cytokine cks-Tg-g-GM-SE0500 transforming growth factor, beta receptor III (TGFBR3) protein & antibody
    ORF Viral Vector pGMLP001368 Human TGFBR3 Lentivirus plasmid
    ORF Viral Vector pGMLP005469 Human TGFBR3 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-042 Human TGFBR3 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-182 Human TGFBR3 Adenovirus plasmid
    ORF Viral Vector vGMLP001368 Human TGFBR3 Lentivirus particle
    ORF Viral Vector vGMLP005469 Human TGFBR3 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-042 Human TGFBR3 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-182 Human TGFBR3 Adenovirus particle


    Target information

    Target ID GM-SE0500
    Target Name TGFBR3
    Gene ID 7049, 21814, 705053, 29610, 101096404, 490163, 784894, 100060435
    Gene Symbol and Synonyms 1110036H20Rik,betaglycan,BGCAN,TBRIII,TGFBR3
    Uniprot Accession Q03167
    Uniprot Entry Name TGBR3_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000069702
    Target Classification Tumor-associated antigen (TAA)

    This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.