Human TGFBR1/AAT5/ACVRLK4 ORF/cDNA clone-Adenovirus particle (NM_004612)

Cat. No.: vGMAP-SPh-180

Pre-made Human TGFBR1/AAT5/ACVRLK4 Adenovirus for TGFBR1 overexpression in-vitro and in-vivo. The TGFBR1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified TGFBR1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAP-SPh-180 Human TGFBR1 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAP-SPh-180
Gene Name TGFBR1
Accession Number NM_004612
Gene ID 7046
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 1512 bp
Gene Alias AAT5,ACVRLK4,ALK-5,ALK5,ESS1,LDS1,LDS1A,LDS2A,MSSE,SKR4,tbetaR-I,TGFR-1
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T53389-Ab Anti-TGFR1/ TGFBR1/ AAT5 monoclonal antibody
    Target Antigen GM-Tg-g-T53389-Ag TGFBR1 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T53389 transforming growth factor, beta receptor 1 (TGFBR1) protein & antibody
    ORF Viral Vector pGMLP001434 Human TGFBR1 Lentivirus plasmid
    ORF Viral Vector pGMLP005234 Human TGFBR1 Lentivirus plasmid
    ORF Viral Vector pGMLP005816 Human TGFBR1 Lentivirus plasmid
    ORF Viral Vector pGMLV001800 Human TGFBR1 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-040 Human TGFBR1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-180 Human TGFBR1 Adenovirus plasmid
    ORF Viral Vector pGMPC000232 Human TGFBR1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001077 Human TGFBR1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001434 Human TGFBR1 Lentivirus particle
    ORF Viral Vector vGMLP005234 Human TGFBR1 Lentivirus particle
    ORF Viral Vector vGMLP005816 Human TGFBR1 Lentivirus particle
    ORF Viral Vector vGMLV001800 Human TGFBR1 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-040 Human TGFBR1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-180 Human TGFBR1 Adenovirus particle


    Target information

    Target ID GM-T53389
    Target Name TGFBR1
    Gene ID 7046, 21812, 714952, 29591, 101094057, 481628, 282382, 100034117
    Gene Symbol and Synonyms AAT5,ACVRLK4,ALK-5,ALK5,ESK2,ESS1,LDS1,LDS1A,LDS2A,MSSE,SKR4,tbetaR-I,TbetaRI,TBR-i,TBRI,TGFBR1,TGFR-1
    Uniprot Accession P36897
    Uniprot Entry Name TGFR1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000106799
    Target Classification Checkpoint-Immuno Oncology, Kinase, Tumor-associated antigen (TAA)

    The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.