Human FLT1/FLT/FLT-1 ORF/cDNA clone-Adenovirus particle (NM_002019.4)
Cat. No.: vGMAD000439
Pre-made Human FLT1/FLT/FLT-1 Adenovirus for FLT1 overexpression in-vitro and in-vivo. The FLT1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified FLT1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
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Product information
Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
vGMAD000439 | Human FLT1 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
5E+10PFU (1E+10pfu/ml×5ml) | |||
1E+11PFU (1E+10pfu/ml×10ml) | |||
Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAD000439 |
Gene Name | FLT1 |
Accession Number | NM_002019.4 |
Gene ID | 2321 |
Species | Human |
Product Type | Adenovirus particle (overexpression) |
Insert Length | 4017 bp |
Gene Alias | FLT,FLT-1,VEGFR-1,VEGFR1 |
Fluorescent Reporter | GFP |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | EF1 |
Resistance | Amplicin |
Reference
Data / case study
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Associated products
Target information
Target ID | GM-T63966 |
Target Name | FLT-1 |
Gene ID | 2321, 14254, 574133, 54251, 101088292, 403727, 503620, 100033957 |
Gene Symbol and Synonyms | FLT,FLT-1,FLT1,sFlt1,VEGFR-1,VEGFR1 |
Uniprot Accession | P17948 |
Uniprot Entry Name | VGFR1_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target |
Disease | Breast Cancer |
Gene Ensembl | ENSG00000102755 |
Target Classification | Checkpoint-Immuno Oncology, Kinase |
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.