Human CXCL12/IRH/PBSF ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_000609)

Cat. No.: vGMAAV000139

Pre-made Human CXCL12/IRH/PBSF Adeno-associated virus particle for CXCL12 in-vivo study, mechanism of action (MOA) research and CXCL12-associated gene therapy development.

At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.

Target products collection

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name AAV serotype AAV Grade AAV quantity
vGMAAV000139 Human CXCL12 Adeno-associate virus(AAV) particle AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF Pilot Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
Research Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAAV000139
Gene Name CXCL12
Accession Number NM_000609
Gene ID 6387
Species Human
Product Type Adeno-associate virus(AAV) particle (overexpression)
Insert Length 282 bp
Gene Alias IRH,PBSF,SCYB12,SDF1,TLSF,TPAR1
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T04773-Ab Anti-SDF1/ CXCL12/ IRH functional antibody
    Target Antigen GM-Tg-g-T04773-Ag CXCL12 protein
    Cytokine cks-Tg-g-GM-T04773 chemokine (C-X-C motif) ligand 12 (CXCL12) protein & antibody
    ORF Viral Vector pGMLV000007 Human CXCL12 Lentivirus plasmid
    ORF Viral Vector pGMLV000955 Human CXCL12 Lentivirus plasmid
    ORF Viral Vector pGMLV002285 Human CXCL12 Lentivirus plasmid
    ORF Viral Vector pGMAD000581 Human CXCL12 Adenovirus plasmid
    ORF Viral Vector pGMAAV000139 Human CXCL12 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAP000581 Human CXCL12 Adenovirus plasmid
    ORF Viral Vector pGMPC001800 Human CXCL12 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000007 Human CXCL12 Lentivirus particle
    ORF Viral Vector vGMLV000955 Human CXCL12 Lentivirus particle
    ORF Viral Vector vGMLV002285 Human CXCL12 Lentivirus particle
    ORF Viral Vector vGMAD000581 Human CXCL12 Adenovirus particle
    ORF Viral Vector vGMAAV000139 Human CXCL12 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAP000581 Human CXCL12 Adenovirus particle


    Target information

    Target ID GM-T04773
    Target Name CXCL12
    Gene ID 6387, 20315, 574334, 24772, 493806, 449622, 613811, 100049872
    Gene Symbol and Synonyms CXCL12,IRH,PBSF,SCYB12,SDF-1,SDF1,TLSF,TPAR1
    Uniprot Accession P48061
    Uniprot Entry Name SDF1_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Immuno-oncology Target, Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000107562
    Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)

    This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.