Human COLEC11/3MC2/CL-11 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001255985)

Cat. No.: pGMPC004783
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human COLEC11/3MC2/CL-11 Non-Viral expression plasmid (overexpression vector) for mouse COLEC11 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC004783
Gene Name COLEC11
Accession Number NM_001255985
Gene ID 78989
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 858 bp
Gene Alias 3MC2,CL-11,CL-K1-I,CL-K1-II,CL-K1-IIa,CL-K1-IIb,CLK1
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGAAGAAACAAAGAGGAGTTGGTGTCCTGCCTGCGCTCAGGATGAGGGGGAATCTGGCCCTGGTGGGCGTTCTAATCAGCCTGGCCTTCCTGTCACTGCTGCCATCTGGACATCCTCAGCCGGCTGGCGATGACGCCTGCTCTGTGCAGATCCTCGTCCCTGGCCTCAAAGGGGATGCGGGAGAGAAGGGAGACAAAGGCGCCCCCGGACGGCCTGGAAGAGTCGGCCCCACGGGAGAAAAAGGAGACATGGGGGACAAAGGACAGAAAGGCAGTGTGGGTCGTCATGGAAAAATTGGTCCCATTGGCTCTAAAGGTGAGAAAGGAGATTCCGGTGACATAGGACCCCCTGGTCCTAATGGAGAACCAGGCCTCCCATGTGAGTGCAGCCAGCTGCGCAAGGCCATCGGGGAGATGGACAACCAGGTCTCTCAGCTGACCAGCGAGCTCAAGTTCATCAAGAATGCTGTCGCCGGTGTGCGCGAGACGGAGAGCAAGATCTACCTGCTGGTGAAGGAGGAGAAGCGCTACGCGGACGCCCAGCTGTCCTGCCAGGGCCGCGGGGGCACGCTGAGCATGCCCAAGGACGAGGCTGCCAATGGCCTGATGGCCGCATACCTGGCGCAAGCCGGCCTGGCCCGTGTCTTCATCGGCATCAACGACCTGGAGAAGGAGGGCGCCTTCGTGTACTCTGACCACTCCCCCATGCGGACCTTCAACAAGTGGCGCAGCGGTGAGCCCAACAATGCCTACGACGAGGAGGACTGCGTGGAGATGGTGGCCTCGGGCGGCTGGAACGACGTGGCCTGCCACACCACCATGTACTTCATGTGTGAGTTTGACAAGGAGAACATGTGA
ORF Protein Sequence MKKQRGVGVLPALRMRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYFMCEFDKENM

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0808-Ab Anti-COL11/ COLEC11/ 3MC2 functional antibody
    Target Antigen GM-Tg-g-SE0808-Ag COLEC11 protein
    ORF Viral Vector pGMLP004916 Human COLEC11 Lentivirus plasmid
    ORF Viral Vector pGMPC004783 Human COLEC11 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP004916 Human COLEC11 Lentivirus particle


    Target information

    Target ID GM-SE0808
    Target Name COLEC11
    Gene ID 78989, 71693, 707223, 366588, 101091014, 482958, 613991, 100072828
    Gene Symbol and Synonyms 3MC2,CL-11,CL-K1,CL-K1-I,CL-K1-II,CL-K1-IIa,CL-K1-IIb,CLK1,COLEC11
    Uniprot Accession Q9BWP8
    Uniprot Entry Name COL11_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000118004
    Target Classification Not Available

    This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]



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