Human NTRK2/DEE58/EIEE58 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001018064.3)

Cat. No.: pGMPC001521
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human NTRK2/DEE58/EIEE58 Non-Viral expression plasmid (overexpression vector) for mouse NTRK2 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001521
Gene Name NTRK2
Accession Number NM_001018064.3
Gene ID 4915
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 2469 bp
Gene Alias DEE58,EIEE58,GP145-TrkB,OBHD,trk-B,TRKB
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T84703-Ab Anti-NTRK2/ TrkB/ EIEE58 monoclonal antibody
    Target Antigen GM-Tg-g-T84703-Ag TrkB/NTRK2 VLP (virus-like particle)
    ORF Viral Vector pGMLP005340 Human NTRK2 Lentivirus plasmid
    ORF Viral Vector pGMLV000193 Human NTRK2 Lentivirus plasmid
    ORF Viral Vector pGMLV000514 Human NTRK2 Lentivirus plasmid
    ORF Viral Vector pGMLV002054 Human NTRK2 Lentivirus plasmid
    ORF Viral Vector pGMAP000431 Human NTRK2 Adenovirus plasmid
    ORF Viral Vector pGMPC001521 Human NTRK2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005340 Human NTRK2 Lentivirus particle
    ORF Viral Vector vGMLV000193 Human NTRK2 Lentivirus particle
    ORF Viral Vector vGMLV000514 Human NTRK2 Lentivirus particle
    ORF Viral Vector vGMLV002054 Human NTRK2 Lentivirus particle
    ORF Viral Vector vGMAP000431 Human NTRK2 Adenovirus particle


    Target information

    Target ID GM-T84703
    Target Name TrkB
    Gene ID 4915, 18212, 709757, 25054, 101101347, 484147, 505824, 100061700
    Gene Symbol and Synonyms DEE58,EIEE58,GP145-TrkB,GP145-TrkB/GP95-TrkB,NTRK2,OBHD,RATTRKB1,Tkrb,trk-B,TRKB,TRKB1
    Uniprot Accession Q16620
    Uniprot Entry Name NTRK2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000148053
    Target Classification Kinase, Tumor-associated antigen (TAA)

    This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]



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