Human FGFR4/CD334/JTK2 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_213647.3)
Cat. No.: pGMPC001430
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human FGFR4/CD334/JTK2 Non-Viral expression plasmid (overexpression vector) for mouse FGFR4 overexpression in unique cell transient transfection and stable cell line development.
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Product Description
Catalog ID | pGMPC001430 |
Gene Name | FGFR4 |
Accession Number | NM_213647.3 |
Gene ID | 2264 |
Species | Human |
Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
Insert Length | 2409 bp |
Gene Alias | CD334,JTK2,TKF |
Fluorescent Reporter | Null |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Biosimilar | GMP-Bios-INN-727 | Pre-Made Aldafermin Biosimilar, Recombinant Protein targeting FGFR4: Recombinant therapeutic protein targeting CD334/JTK2/TKF |
Target Antibody | GM-Tg-g-T90989-Ab | Anti-FGFR4/ CD334/ JTK2 monoclonal antibody |
Target Antigen | GM-Tg-g-T90989-Ag | FGFR4 VLP (virus-like particle) |
Cytokine | cks-Tg-g-GM-T90989 | Fibroblast growth factor receptor 4 (FGFR4) protein & antibody |
ORF Viral Vector | pGMLP005640 | Human FGFR4 Lentivirus plasmid |
ORF Viral Vector | pGMLV000558 | Human FGFR4 Lentivirus plasmid |
ORF Viral Vector | pGMPC001430 | Human FGFR4 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMLP005640 | Human FGFR4 Lentivirus particle |
ORF Viral Vector | vGMLV000558 | Human FGFR4 Lentivirus particle |
Target information
Target ID | GM-T90989 |
Target Name | FGFR4 |
Gene ID | 2264, 14186, 698494, 25114, 101100864, 489095, 317696, 100068679 |
Gene Symbol and Synonyms | CD334,Fgfr-4,FGFR4,JTK2,TKF |
Uniprot Accession | P22455 |
Uniprot Entry Name | FGFR4_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, INN Index, Cytokine Target |
Disease | Breast Cancer, Ovary Cancer |
Gene Ensembl | ENSG00000160867 |
Target Classification | Kinase |
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.