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Human EGFR/ERBB/ERBB1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_005228.4)
Cat. No.: pGMPC001179
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human EGFR/ERBB/ERBB1 Non-Viral expression plasmid (overexpression vector) for mouse EGFR overexpression in unique cell transient transfection and stable cell line development.
Datasheet
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Product Description
| Catalog ID | pGMPC001179 |
| Gene Name | EGFR |
| Accession Number | NM_005228.4 |
| Gene ID | 1956 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 3633 bp |
| Gene Alias | ERBB,ERBB1,HER1,mENA,NISBD2,PIG61 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
Reference
Data / case study
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Associated products
Target information
| Target ID | GM-T59328 |
| Target Name | EGFR |
| Gene ID | 1956, 13649, 613027, 24329, 100510799, 404306, 407217, 100067755 |
| Gene Symbol and Synonyms | 9030024J15Rik,EGFR,ERBB,ErbB-1,ERBB1,Errb1,ERRP,HER1,mENA,NISBD2,PIG61,wa-2,wa2,Wa5 |
| Uniprot Accession | P00533 |
| Uniprot Entry Name | EGFR_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target |
| Disease | Breast Cancer, Non-Small Cell Lung Cancer, gastric cancer, apoptosis, Asphyxia neonatorum, Urinary bladder urothelial carcinoma |
| Gene Ensembl | ENSG00000146648 |
| Target Classification | Checkpoint-Immuno Oncology, Kinase |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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