Human MANBA/MANB1 ORF/cDNA clone-Lentivirus plasmid (NM_005908.4)

Cat. No.: pGMLV002344
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human MANBA/MANB1 Lentiviral expression plasmid for MANBA lentivirus packaging, MANBA lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV002344
Gene Name MANBA
Accession Number NM_005908.4
Gene ID 4126
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2640 bp
Gene Alias MANB1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCGCCTCCACCTGCTCCTGCTGCTCGCGCTGTGCGGTGCAGGCACCACCGCCGCGGAGCTCAGTTACAGCTTGCGTGGCAACTGGAGCATCTGCAATGGGAACGGCTCGCTGGAGCTGCCCGGGGCGGTCCCTGGCTGCGTGCACAGCGCCTTGTTCCAGCAGGGCCTGATCCAGGATTCTTACTACAGATTTAATGACCTTAACTACAGATGGGTCTCTTTGGATAACTGGACCTATAGCAAAGAATTTAAAATCCCCTTTGAAATTAGCAAATGGCAAAAAGTAAATTTGATTCTTGAGGGAGTGGATACGGTTTCAAAAATCCTGTTCAATGAAGTCACTATTGGGGAAACAGACAATATGTTCAATAGATATAGCTTTGATATTACCAACGTGGTCAGGGACGTGAACTCCATTGAGCTGCGTTTCCAGTCAGCGGTGTTGTATGCAGCACAGCAGAGCAAAGCTCACACTCGCTACCAGGTTCCCCCAGACTGCCCTCCACTTGTGCAGAAGGGTGAATGCCATGTCAACTTTGTTCGGAAGGAGCAATGTTCCTTTAGTTGGGACTGGGGGCCTTCCTTTCCTACCCAGGGAATCTGGAAAGATGTTAGAATTGAAGCCTATAATATTTGTCACCTGAACTACTTCACATTTTCCCCAATATATGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGA
ORF Protein Sequence MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQDSYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETDNMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNFVRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2583-Ab Anti-MANBA/ MANB1 monoclonal antibody
    Target Antigen GM-Tg-g-MP2583-Ag MANBA VLP (virus-like particle)
    ORF Viral Vector pGMLV002344 Human MANBA Lentivirus plasmid
    ORF Viral Vector vGMLV002344 Human MANBA Lentivirus particle


    Target information

    Target ID GM-MP2583
    Target Name MANBA
    Gene ID 4126, 110173, 712531, 310864, 101085628, 487883, 281909, 100067947
    Gene Symbol and Synonyms 2410030O07Rik,B930014J03Rik,Bmn,MANB1,MANBA
    Uniprot Accession O00462
    Uniprot Entry Name MANBA_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000109323
    Target Classification Not Available

    This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008]



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