Human TNFAIP3/A20/AISBL ORF/cDNA clone-Lentivirus plasmid (NM_001270508.1)

SKU: pGMLV000596
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TNFAIP3/A20/AISBL Lentiviral expression plasmid for TNFAIP3 lentivirus packaging, TNFAIP3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000596
Gene Name TNFAIP3
Accession Number NM_001270508.1
Gene ID 7128
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2373 bp
Gene Alias A20,AISBL,OTUD7C,TNFA1P2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T56474-Ab Anti-TNFAIP3 monoclonal antibody
    Target Antigen GM-Tg-g-T56474-Ag TNFAIP3 protein
    Cytokine cks-Tg-g-GM-T56474 tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) protein & antibody
    ORF Viral Vector pGMLV000596 Human TNFAIP3 Lentivirus plasmid
    ORF Viral Vector pGMLV002333 Human TNFAIP3 Lentivirus plasmid
    ORF Viral Vector vGMLV000596 Human TNFAIP3 Lentivirus particle
    ORF Viral Vector vGMLV002333 Human TNFAIP3 Lentivirus particle


    Target information

    Target ID GM-T56474
    Target Name TNFAIP3
    Gene ID 7128, 21929, 704130, 683206, 101083682, 484006, 508105, 100073197
    Gene Symbol and Synonyms A20,AIFBL1,AISBL,OTUD7C,TNFA1P2,TNFAIP3,Tnfip3
    Uniprot Accession P21580
    Uniprot Entry Name TNAP3_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Cytokine Target
    Disease IgA glomerulonephritis
    Gene Ensembl ENSG00000118503
    Target Classification Not Available

    This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]



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