Human FZD7/FzE3 ORF/cDNA clone-Lentivirus plasmid (NM_003507.1)

Cat. No.: pGMLV000582
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human FZD7/FzE3 Lentiviral expression plasmid for FZD7 lentivirus packaging, FZD7 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000582
Gene Name FZD7
Accession Number NM_003507.1
Gene ID 8324
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1725 bp
Gene Alias FzE3
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T39797-Ab Anti-FZD7/ FzE3 monoclonal antibody
    Target Antigen GM-Tg-g-T39797-Ag FZD7 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T39797 frizzled class receptor 7 (FZD7) protein & antibody
    ORF Viral Vector pGMLV000582 Human FZD7 Lentivirus plasmid
    ORF Viral Vector vGMLV000582 Human FZD7 Lentivirus particle


    Target information

    Target ID GM-T39797
    Target Name FZD7
    Gene ID 8324, 14369, 703064, 100360552, 101087255, 488478, 524255, 102147960
    Gene Symbol and Synonyms Fz7,FZD7,FzE3
    Uniprot Accession O75084
    Uniprot Entry Name FZD7_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Cytokine Target
    Disease Not Available
    Gene Ensembl ENSG00000155760
    Target Classification Not Available

    Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.  The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.  FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]



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