Human NTRK1/MTC/p140-TrkA ORF/cDNA clone-Lentivirus plasmid (NM_002529)

SKU: pGMLV000500
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human NTRK1/MTC/p140-TrkA Lentiviral expression plasmid for NTRK1 lentivirus packaging, NTRK1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000500
Gene Name NTRK1
Accession Number NM_002529
Gene ID 4914
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2391 bp
Gene Alias MTC,p140-TrkA,TRK,Trk-A,TRK1,TRKA
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T07173-Ab Anti-NTRK1/ TrkA/ MTC monoclonal antibody
    Target Antigen GM-Tg-g-T07173-Ag TrkA/NTRK1 VLP (virus-like particle)
    ORF Viral Vector pGMLP005346 Human NTRK1 Lentivirus plasmid
    ORF Viral Vector pGMLV000283 Human NTRK1 Lentivirus plasmid
    ORF Viral Vector pGMLV000500 Human NTRK1 Lentivirus plasmid
    ORF Viral Vector pGMLV000501 Human NTRK1 Lentivirus plasmid
    ORF Viral Vector vGMLP005346 Human NTRK1 Lentivirus particle
    ORF Viral Vector vGMLV000283 Human NTRK1 Lentivirus particle
    ORF Viral Vector vGMLV000500 Human NTRK1 Lentivirus particle
    ORF Viral Vector vGMLV000501 Human NTRK1 Lentivirus particle


    Target information

    Target ID GM-T07173
    Target Name TrkA
    Gene ID 4914, 18211, 719670, 59109, 101081603, 490404, 353111, 100064594
    Gene Symbol and Synonyms MTC,NTRK1,p140-TrkA,Tkr,TRK,Trk-A,TRK1,TRKA
    Uniprot Accession P04629
    Uniprot Entry Name NTRK1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000198400
    Target Classification Kinase, Tumor-associated antigen (TAA)

    This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]



    About GMVC

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