Human NTRK3/gp145(trkC)/GP145-TrkC ORF/cDNA clone-Lentivirus plasmid (NM_001012338.2)

Cat. No.: pGMLV000469
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human NTRK3/gp145(trkC)/GP145-TrkC Lentiviral expression plasmid for NTRK3 lentivirus packaging, NTRK3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000469
Gene Name NTRK3
Accession Number NM_001012338.2
Gene ID 4916
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2520 bp
Gene Alias gp145(trkC),GP145-TrkC,TRKC
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence 正确

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T51076-Ab Anti-NTRK3/ TrkC/ GP145-TrkC monoclonal antibody
    Target Antigen GM-Tg-g-T51076-Ag TrkC/NTRK3 VLP (virus-like particle)
    ORF Viral Vector pGMLP005352 Human NTRK3 Lentivirus plasmid
    ORF Viral Vector pGMLV000469 Human NTRK3 Lentivirus plasmid
    ORF Viral Vector vGMLP005352 Human NTRK3 Lentivirus particle
    ORF Viral Vector vGMLV000469 Human NTRK3 Lentivirus particle


    Target information

    Target ID GM-T51076
    Target Name TrkC
    Gene ID 4916, 18213, 697615, 29613, 101085548, 100856261, 539126, 100069852
    Gene Symbol and Synonyms gp145(trkC),GP145-TrkC,NTRK3,Ntrk3_tv3,TRKC
    Uniprot Accession Q16288
    Uniprot Entry Name NTRK3_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000140538
    Target Classification Kinase, Tumor-associated antigen (TAA)

    This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]



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