Human CCR9/CC-CKR-9/CDw199 ORF/cDNA clone-Lentivirus plasmid (NM_031200.2)
SKU: pGMLV000052
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human CCR9/CC-CKR-9/CDw199 Lentiviral expression plasmid for CCR9 lentivirus packaging, CCR9 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product Description
Catalog ID | pGMLV000052 |
Gene Name | CCR9 |
Accession Number | NM_031200.2 |
Gene ID | 10803 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 1110 bp |
Gene Alias | CC-CKR-9,CDw199,GPR-9-6,GPR28 |
Fluorescent Reporter | Null |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | Null |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T97873-Ab | Anti-CCR9/ CC-CKR-9/ CDw199 monoclonal antibody |
Target Antigen | GM-Tg-g-T97873-Ag | CCR9 VLP (virus-like particle) |
Cytokine | cks-Tg-g-GM-T97873 | chemokine (C-C motif) receptor 9 (CCR9) protein & antibody |
ORF Viral Vector | pGMLV000052 | Human CCR9 Lentivirus plasmid |
ORF Viral Vector | vGMLV000052 | Human CCR9 Lentivirus particle |
Target information
Target ID | GM-T97873 |
Target Name | CCR9 |
Gene ID | 10803, 12769, 713934, 282832, 101083247, 484793, 530951, 100065535 |
Gene Symbol and Synonyms | A130091K22Rik,CC-CKR-9,CCR9,CDw199,Cmkbr10,GPR-9-6,GPR28 |
Uniprot Accession | P51686 |
Uniprot Entry Name | CCR9_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Immuno-oncology Target, Cytokine Target |
Disease | Not Available |
Gene Ensembl | ENSG00000173585 |
Target Classification | Checkpoint-Immuno Oncology, GPCR |
The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
About GMVC
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