Human TNFSF13/APRIL/CD256 ORF/cDNA clone-Lentivirus plasmid (NM_003808)

Cat. No.: pGMLP005046
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TNFSF13/APRIL/CD256 Lentiviral expression plasmid for TNFSF13 lentivirus packaging, TNFSF13 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP005046
Gene Name TNFSF13
Accession Number NM_003808
Gene ID 8741
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 753 bp
Gene Alias APRIL,CD256,TALL-2,TALL2,TNLG7B,TRDL-1,UNQ383/PRO715,ZTNF2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCAGCCTCATCTCCTTTCTTGCTAGCCCCCAAAGGGCCTCCAGGCAACATGGGGGGCCCAGTCAGAGAGCCGGCACTCTCAGTTGCCCTCTGGTTGAGTTGGGGGGCAGCTCTGGGGGCCGTGGCTTGTGCCATGGCTCTGCTGACCCAACAAACAGAGCTGCAGAGCCTCAGGAGAGAGGTGAGCCGGCTGCAGGGGACAGGAGGCCCCTCCCAGAATGGGGAAGGGTATCCCTGGCAGAGTCTCCCGGAGCAGAGTTCCGATGCCCTGGAAGCCTGGGAGAATGGGGAGAGATCCCGGAAAAGGAGAGCAGTGCTCACCCAAAAACAGAAGAAGCAGCACTCTGTCCTGCACCTGGTTCCCATTAACGCCACCTCCAAGGATGACTCCGATGTGACAGAGGTGATGTGGCAACCAGCTCTTAGGCGTGGGAGAGGCCTACAGGCCCAAGGATATGGTGTCCGAATCCAGGATGCTGGAGTTTATCTGCTGTATAGCCAGGTCCTGTTTCAAGACGTGACTTTCACCATGGGTCAGGTGGTGTCTCGAGAAGGCCAAGGAAGGCAGGAGACTCTATTCCGATGTATAAGAAGTATGCCCTCCCACCCGGACCGGGCCTACAACAGCTGCTATAGCGCAGGTGTCTTCCATTTACACCAAGGGGATATTCTGAGTGTCATAATTCCCCGGGCAAGGGCGAAACTTAACCTCTCTCCACATGGAACCTTCCTGGGGTTTGTGAAACTGTGA
ORF Protein Sequence MPASSPFLLAPKGPPGNMGGPVREPALSVALWLSWGAALGAVACAMALLTQQTELQSLRREVSRLQGTGGPSQNGEGYPWQSLPEQSSDALEAWENGERSRKRRAVLTQKQKKQHSVLHLVPINATSKDDSDVTEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSREGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVFHLHQGDILSVIIPRARAKLNLSPHGTFLGFVKL

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-518 Pre-Made Sibeprenlimab biosimilar, Whole mAb, Anti-TNFSF13/APRIL Antibody: Anti-CD256/TALL-2/TALL2/TNLG7B/TRDL-1/UNQ383/PRO715/ZTNF2 therapeutic antibody
    Biosimilar GMP-Bios-INN-742 Pre-Made Atacicept Biosimilar, Fusion Protein targeting TNFSF13/APRIL fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting CD256/TALL-2/TALL2/TNLG7B/TRDL-1/UNQ383/PRO715/ZTNF2
    Target Antibody GM-Tg-g-T14676-Ab Anti-TNF13/ APRIL/ TNFSF13 functional antibody
    Target Antigen GM-Tg-g-T14676-Ag APRIL/TNFSF13 protein
    Cytokine cks-Tg-g-GM-T14676 tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13) protein & antibody
    ORF Viral Vector pGMLP005046 Human TNFSF13 Lentivirus plasmid
    ORF Viral Vector vGMLP005046 Human TNFSF13 Lentivirus particle


    Target information

    Target ID GM-T14676
    Target Name APRIL
    Gene ID 8741, 69583, 100551507, 287437, 100328582, 100568281, 538567, 100147233
    Gene Symbol and Synonyms 2310026N09Rik,APRIL,CD256,TALL-2,TALL2,TNFSF13,TNLG7B,TRDL-1,Trdl1,UNQ383/PRO715,ZTNF2
    Uniprot Accession O75888
    Uniprot Entry Name TNF13_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
    Disease Lupus Glomerulonephritis
    Gene Ensembl ENSG00000161955
    Target Classification Checkpoint-Immuno Oncology

    The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]



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