Human CALCRL/CGRPR/CRLR ORF/cDNA clone-Lentivirus plasmid (NM_005795)

Cat. No.: pGMLP003725
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CALCRL/CGRPR/CRLR Lentiviral expression plasmid for CALCRL lentivirus packaging, CALCRL lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003725
Gene Name CALCRL
Accession Number NM_005795
Gene ID 10203
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1386 bp
Gene Alias CGRPR,CRLR
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGAAAAAGTGTACCCTGTATTTTCTGGTTCTCTTGCCTTTTTTTATGATTCTTGTTACAGCAGAATTAGAAGAGAGTCCTGAGGACTCAATTCAGTTGGGAGTTACTAGAAATAAAATCATGACAGCTCAATATGAATGTTACCAAAAGATTATGCAAGACCCCATTCAACAAGCAGAAGGCGTTTACTGCAACAGAACCTGGGATGGATGGCTCTGCTGGAACGATGTTGCAGCAGGAACTGAATCAATGCAGCTCTGCCCTGATTACTTTCAGGACTTTGATCCATCAGAAAAAGTTACAAAGATCTGTGACCAAGATGGAAACTGGTTTAGACATCCAGCAAGCAACAGAACATGGACAAATTATACCCAGTGTAATGTTAACACCCACGAGAAAGTGAAGACTGCACTAAATTTGTTTTACCTGACCATAATTGGACACGGATTGTCTATTGCATCACTGCTTATCTCGCTTGGCATATTCTTTTATTTCAAGAGCCTAAGTTGCCAAAGGATTACCTTACACAAAAATCTGTTCTTCTCATTTGTTTGTAACTCTGTTGTAACAATCATTCACCTCACTGCAGTGGCCAACAACCAGGCCTTAGTAGCCACAAATCCTGTTAGTTGCAAAGTGTCCCAGTTCATTCATCTTTACCTGATGGGCTGTAATTACTTTTGGATGCTCTGTGAAGGCATTTACCTACACACACTCATTGTGGTGGCCGTGTTTGCAGAGAAGCAACATTTAATGTGGTATTATTTTCTTGGCTGGGGATTTCCACTGATTCCTGCTTGTATACATGCCATTGCTAGAAGCTTATATTACAATGACAATTGCTGGATCAGTTCTGATACCCATCTCCTCTACATTATCCATGGCCCAATTTGTGCTGCTTTACTGGTGAATCTTTTTTTCTTGTTAAATATTGTACGCGTTCTCATCACCAAGTTAAAAGTTACACACCAAGCGGAATCCAATCTGTACATGAAAGCTGTGAGAGCTACTCTTATCTTGGTGCCATTGCTTGGCATTGAATTTGTGCTGATTCCATGGCGACCTGAAGGAAAGATTGCAGAGGAGGTATATGACTACATCATGCACATCCTTATGCACTTCCAGGGTCTTTTGGTCTCTACCATTTTCTGCTTCTTTAATGGAGAGGTTCAAGCAATTCTGAGAAGAAACTGGAATCAATACAAAATCCAATTTGGAAACAGCTTTTCCAACTCAGAAGCTCTTCGTAGTGCGTCTTACACAGTGTCAACAATCAGTGATGGTCCAGGTTATAGTCATGACTGTCCTAGTGAACACTTAAATGGAAAAAGCATCCATGATATTGAAAATGTTCTCTTAAAACCAGAAAATTTATATAATTGA
ORF Protein Sequence MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-193 Pre-Made Erenumab biosimilar, Whole mAb, Anti-CALCRL/CGRPR Antibody: Anti-CRLR/LMPHM8 therapeutic antibody
    Target Antibody GM-Tg-g-T32262-Ab Anti-CALRL/ CGRPR/ CALCRL monoclonal antibody
    Target Antigen GM-Tg-g-T32262-Ag CGRPR/CALCRL VLP (virus-like particle)
    ORF Viral Vector pGMLP003725 Human CALCRL Lentivirus plasmid
    ORF Viral Vector vGMLP003725 Human CALCRL Lentivirus particle


    Target information

    Target ID GM-T32262
    Target Name CGRPR
    Gene ID 10203, 54598, 708187, 25029, 101086333, 488438, 527140, 100054281
    Gene Symbol and Synonyms CALCRL,CGRPR,CLR,CRLR,LMPHM8,RATCRLR,RNCLR
    Uniprot Accession Q16602
    Uniprot Entry Name CALRL_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, INN Index
    Disease Not Available
    Gene Ensembl ENSG00000064989
    Target Classification Not Available

    Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022]



    About GMVC

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