Human CX3CR1/CCRL1/CMKBRL1 ORF/cDNA clone-Lentivirus plasmid (NM_001337.3)

SKU: pGMLP001885
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CX3CR1/CCRL1/CMKBRL1 Lentiviral expression plasmid for CX3CR1 lentivirus packaging, CX3CR1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP001885
Gene Name CX3CR1
Accession Number NM_001337.3
Gene ID 1524
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1068 bp
Gene Alias CCRL1,CMKBRL1,CMKDR1,GPR13,GPRV28,V28
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence ATGGATCAGTTCCCTGAATCAGTGACAGAAAACTTTGAGTACGATGATTTGGCTGAGGCCTGTTATATTGGGGACATCGTGGTCTTTGGGACTGTGTTCCTGTCCATATTCTACTCCGTCATCTTTGCCATTGGCCTGGTGGGAAATTTGTTGGTAGTGTTTGCCCTCACCAACAGCAAGAAGCCCAAGAGTGTCACCGACATTTACCTCCTGAACCTGGCCTTGTCTGATCTGCTGTTTGTAGCCACTTTGCCCTTCTGGACTCACTATTTGATAAATGAAAAGGGCCTCCACAATGCCATGTGCAAATTCACTACCGCCTTCTTCTTCATCGGCTTTTTTGGAAGCATATTCTTCATCACCGTCATCAGCATTGATAGGTACCTGGCCATCGTCCTGGCCGCCAACTCCATGAACAACCGGACCGTGCAGCATGGCGTCACCATCAGCCTAGGCGTCTGGGCAGCAGCCATTTTGGTGGCAGCACCCCAGTTCATGTTCACAAAGCAGAAAGAAAATGAATGCCTTGGTGACTACCCCGAGGTCCTCCAGGAAATCTGGCCCGTGCTCCGCAATGTGGAAACAAATTTTCTTGGCTTCCTACTCCCCCTGCTCATTATGAGTTATTGCTACTTCAGAATCATCCAGACGCTGTTTTCCTGCAAGAACCACAAGAAAGCCAAAGCCATTAAACTGATCCTTCTGGTGGTCATCGTGTTTTTCCTCTTCTGGACACCCTACAACGTTATGATTTTCCTGGAGACGCTTAAGCTCTATGACTTCTTTCCCAGTTGTGACATGAGGAAGGATCTGAGGCTGGCCCTCAGTGTGACTGAGACGGTTGCATTTAGCCATTGTTGCCTGAATCCTCTCATCTATGCATTTGCTGGGGAGAAGTTCAGAAGATACCTTTACCACCTGTATGGGAAATGCCTGGCTGTCCTGTGTGGGCGCTCAGTCCACGTTGATTTCTCCTCATCTGAATCACAAAGGAGCAGGCATGGAAGTGTTCTGAGCAGCAATTTTACTTACCACACGAGTGATGGAGATGCATTGCTCCTTCTCTGA

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T15033-Ab Anti-CX3C1/ CX3CR1/ CCRL1 monoclonal antibody
    Target Antigen GM-Tg-g-T15033-Ag CX3CR1 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T15033 chemokine (C-X3-C motif) receptor 1 (CX3CR1) protein & antibody
    ORF Viral Vector pGMLP001885 Human CX3CR1 Lentivirus plasmid
    ORF Viral Vector vGMLP001885 Human CX3CR1 Lentivirus particle


    Target information

    Target ID GM-T15033
    Target Name CX3CR1
    Gene ID 1524, 13051, 693926, 171056, 101099898, 485599, 100124525, 100068350
    Gene Symbol and Synonyms CCRL1,CMKBRL1,CMKDR1,CX3CR1,GPR13,GPRV28,mCX3CR1,Rbs11,V28
    Uniprot Accession P49238
    Uniprot Entry Name CX3C1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, Cytokine Target
    Disease Not Available
    Gene Ensembl ENSG00000168329
    Target Classification Checkpoint-Immuno Oncology, GPCR

    Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]



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