Human TNFRSF11A/CD265/FEO ORF/cDNA clone-Lentivirus plasmid (NM_003839)

Cat. No.: pGMLP001749
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TNFRSF11A/CD265/FEO Lentiviral expression plasmid for TNFRSF11A lentivirus packaging, TNFRSF11A lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001749
Gene Name TNFRSF11A
Accession Number NM_003839
Gene ID 8792
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1851 bp
Gene Alias CD265,FEO,LOH18CR1,ODFR,OFE,OPTB7,OSTS,PDB2,RANK,TRANCER
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCCCGCGCGCCCGGCGGCGCCGCCCGCTGTTCGCGCTGCTGCTGCTCTGCGCGCTGCTCGCCCGGCTGCAGGTGGCTTTGCAGATCGCTCCTCCATGTACCAGTGAGAAGCATTATGAGCATCTGGGACGGTGCTGTAACAAATGTGAACCAGGAAAGTACATGTCTTCTAAATGCACTACTACCTCTGACAGTGTATGTCTGCCCTGTGGCCCGGATGAATACTTGGATAGCTGGAATGAAGAAGATAAATGCTTGCTGCATAAAGTTTGTGATACAGGCAAGGCCCTGGTGGCCGTGGTCGCCGGCAACAGCACGACCCCCCGGCGCTGCGCGTGCACGGCTGGGTACCACTGGAGCCAGGACTGCGAGTGCTGCCGCCGCAACACCGAGTGCGCGCCGGGCCTGGGCGCCCAGCACCCGTTGCAGCTCAACAAGGACACAGTGTGCAAACCTTGCCTTGCAGGCTACTTCTCTGATGCCTTTTCCTCCACGGACAAATGCAGACCCTGGACCAACTGTACCTTCCTTGGAAAGAGAGTAGAACATCATGGGACAGAGAAATCCGATGCGGTTTGCAGTTCTTCTCTGCCAGCTAGAAAACCACCAAATGAACCCCATGTTTACTTGCCCGGTTTAATAATTCTGCTTCTCTTCGCGTCTGTGGCCCTGGTGGCTGCCATCATCTTTGGCGTTTGCTATAGGAAAAAAGGGAAAGCACTCACAGCTAATTTGTGGCACTGGATCAATGAGGCTTGTGGCCGCCTAAGTGGAGATAAGGAGTCCTCAGGTGACAGTTGTGTCAGTACACACACGGCAAACTTTGGTCAGCAGGGAGCATGTGAAGGTGTCTTACTGCTGACTCTGGAGGAGAAGACATTTCCAGAAGATATGTGCTACCCAGATCAAGGTGGTGTCTGTCAGGGCACATGTGTAGGAGGTGGTCCCTACGCACAAGGCGAAGATGCCAGGATGCTCTCATTGGTCAGCAAGACCGAGATAGAGGAAGACAGCTTCAGACAGATGCCCACAGAAGATGAATACATGGACAGGCCCTCCCAGCCCACAGACCAGTTACTGTTCCTCACTGAGCCTGGAAGCAAATCCACACCTCCTTTCTCTGAACCCCTGGAGGTGGGGGAGAATGACAGTTTAAGCCAGTGCTTCACGGGGACACAGAGCACAGTGGGTTCAGAAAGCTGCAACTGCACTGAGCCCCTGTGCAGGACTGATTGGACTCCCATGTCCTCTGAAAACTACTTGCAAAAAGAGGTGGACAGTGGCCATTGCCCGCACTGGGCAGCCAGCCCCAGCCCCAACTGGGCAGATGTCTGCACAGGCTGCCGGAACCCTCCTGGGGAGGACTGTGAACCCCTCGTGGGTTCCCCAAAACGTGGACCCTTGCCCCAGTGCGCCTATGGCATGGGCCTTCCCCCTGAAGAAGAAGCCAGCAGGACGGAGGCCAGAGACCAGCCCGAGGATGGGGCTGATGGGAGGCTCCCAAGCTCAGCGAGGGCAGGTGCCGGGTCTGGAAGCTCCCCTGGTGGCCAGTCCCCTGCATCTGGAAATGTGACTGGAAACAGTAACTCCACGTTCATCTCCAGCGGGCAGGTGATGAACTTCAAGGGCGACATCATCGTGGTCTACGTCAGCCAGACCTCGCAGGAGGGCGCGGCGGCGGCTGCGGAGCCCATGGGCCGCCCGGTGCAGGAGGAGACCCTGGCGCGCCGAGACTCCTTCGCGGGGAACGGCCCGCGCTTCCCGGACCCGTGCGGCGGCCCCGAGGGGCTGCGGGAGCCGGAGAAGGCCTCGAGGCCGGTGCAGGAGCAAGGCGGGGCCAAGGCTTGA
ORF Protein Sequence MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQGGAKA

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T85746-Ab Anti-TNR11/ ODFR/ TNFRSF11A monoclonal antibody
    Target Antigen GM-Tg-g-T85746-Ag ODFR/TNFRSF11A VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T85746 tumor necrosis factor receptor superfamily, member 11a, NFKB activator (TNFRSF11A) protein & antibody
    ORF Viral Vector pGMLP001749 Human TNFRSF11A Lentivirus plasmid
    ORF Viral Vector vGMLP001749 Human TNFRSF11A Lentivirus particle


    Target information

    Target ID GM-T85746
    Target Name ODFR
    Gene ID 8792, 21934, 100424175, 498206, 101090651, 483957, 530884, 100056617
    Gene Symbol and Synonyms CD265,FEO,LOH18CR1,Ly109,mRANK,ODFR,OFE,OPTB7,OSTS,PDB2,RANK,RGD1563614,TNFRSF11A,TRANCE-R,TRANCER
    Uniprot Accession Q9Y6Q6
    Uniprot Entry Name TNR11_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000141655
    Target Classification Checkpoint-Immuno Oncology, Pathway, Tumor-associated antigen (TAA)

    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]



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