Human GFRAL/bA360D14.1/C6orf144 ORF/cDNA clone-Lentivirus plasmid (NM_207410)

Cat. No.: pGMLP001654
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human GFRAL/bA360D14.1/C6orf144 Lentiviral expression plasmid for GFRAL lentivirus packaging, GFRAL lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP001654
Gene Name GFRAL
Accession Number NM_207410
Gene ID 389400
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1185 bp
Gene Alias bA360D14.1,C6orf144,GRAL,UNQ9356
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence ATGATAGTGTTTATTTTCTTGGCTATGGGGTTAAGCTTGGAAAATGAATACACTTCCCAAACCAATAATTGCACATATTTAAGAGAGCAATGCTTACGTGATGCAAATGGATGTAAACATGCTTGGAGAGTAATGGAAGATGCCTGCAATGATTCAGATCCAGGTGACCCCTGCAAGATGAGGAATTCATCATACTGTAACCTGAGTATCCAGTACTTAGTGGAAAGCAATTTCCAATTTAAAGAGTGTCTTTGCACTGATGACTTCTATTGTACTGTGAACAAACTGCTTGGAAAAAAATGTATCAATAAATCAGATAACGTGAAAGAGGATAAATTCAAATGGAATCTAACTACACGTTCCCATCATGGATTCAAAGGGATGTGGTCCTGTTTGGAAGTGGCAGAGGCATGTGTAGGGGATGTGGTCTGTAATGCACAGTTGGCCTCTTACCTTAAAGCTTGCTCAGCAAATGGAAATCCGTGTGATCTGAAACAGTGCCAAGCAGCCATACGGTTCTTCTATCAAAATATACCTTTTAACATTGCCCAGATGTTGGCTTTTTGTGACTGTGCTCAATCTGATATACCTTGTCAGCAGTCCAAAGAAGCTCTTCACAGCAAGACATGTGCAGTGAACATGGTTCCACCCCCTACTTGCCTCAGTGTAATTCGCAGCTGCCAAAATGATGAATTATGCAGGAGGCACTATAGAACATTTCAGTCAAAATGCTGGCAGCGTGTGACTAGAAAGTGCCATGAAGATGAGAATTGCATTAGCACCTTAAGCAAACAGGACCTCACTTGTTCAGGAAGTGATGACTGCAAAGCTGCTTACATAGATATCCTTGGGACGGTCCTTCAAGTGCAATGTACCTGTAGGACCATTACACAAAGTGAGGAATCTTTGTGTAAGATTTTCCAGCACATGCTTCATAGAAAATCATGTTTCAATTATCCAACCCTGTCTAATGTCAAAGGCATGGCATTGTATACAAGAAAACATGCAAACAAAATCACTTTAACTGGATTTCATTCCCCCTTCAATGGAGAAGTAATCTATGCTGCCATGTGCATGACAGTCACCTGTGGAATCCTTCTGTTGGTTATGGTCAAGCTTAGAACTTCCAGAATATCAAGTAAAGCAAGAGATCCTTCATCGATCCAAATACCTGGAGAACTCTGA

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T37012-Ab Anti-GFRAL/ C6orf144/ GRAL monoclonal antibody
    Target Antigen GM-Tg-g-T37012-Ag GFRAL VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T37012 GDNF family receptor alpha like (GFRAL) protein & antibody
    ORF Viral Vector pGMLP001654 Human GFRAL Lentivirus plasmid
    ORF Viral Vector pGMLV002346 Human GFRAL Lentivirus plasmid
    ORF Viral Vector vGMLP001654 Human GFRAL Lentivirus particle
    ORF Viral Vector vGMLV002346 Human GFRAL Lentivirus particle


    Target information

    Target ID GM-T37012
    Target Name GFRAL
    Gene ID 389400, 404194, 714935, 501023, 101097066, 481851, 531956, 100069686
    Gene Symbol and Synonyms bA360D14.1,C6orf144,GFRAL,GRAL,RGD1565220,UNQ9356
    Uniprot Accession Q6UXV0
    Uniprot Entry Name GFRAL_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Cytokine Target
    Disease Not Available
    Gene Ensembl ENSG00000187871
    Target Classification Not Available

    Enables glial cell-derived neurotrophic factor receptor activity and receptor tyrosine kinase binding activity. Involved in glial cell-derived neurotrophic factor receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of protein kinase B signaling. Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]



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