Human CCL11/SCYA11 ORF/cDNA clone-Lentivirus plasmid (NM_002986)
Cat. No.: pGMLP000540
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human CCL11/SCYA11 Lentiviral expression plasmid for CCL11 lentivirus packaging, CCL11 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product Description
Catalog ID | pGMLP000540 |
Gene Name | CCL11 |
Accession Number | NM_002986 |
Gene ID | 6356 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 294 bp |
Gene Alias | SCYA11 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGAAGGTCTCCGCAGCACTTCTGTGGCTGCTGCTCATAGCAGCTGCCTTCAGCCCCCAGGGGCTCGCTGGGCCAGCTTCTGTCCCAACCACCTGCTGCTTTAACCTGGCCAATAGGAAGATACCCCTTCAGCGACTAGAGAGCTACAGGAGAATCACCAGTGGCAAATGTCCCCAGAAAGCTGTGATCTTCAAGACCAAACTGGCCAAGGATATCTGTGCCGACCCCAAGAAGAAGTGGGTGCAGGATTCCATGAAGTATCTGGACCAAAAATCTCCAACTCCAAAGCCATAA |
ORF Protein Sequence | MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Biosimilar | GMP-Bios-INN-755 | Pre-Made Bertilimumab Biosimilar, Whole Mab, Anti-Ccl11 Antibody: Anti-SCYA11 therapeutic antibody |
Target Antibody | GM-Tg-g-T16888-Ab | Anti-CCL11/ SCYA11 functional antibody |
Target Antigen | GM-Tg-g-T16888-Ag | CCL11 protein |
Cytokine | cks-Tg-g-GM-T16888 | chemokine (C-C motif) ligand 11 (CCL11) protein & antibody |
ORF Viral Vector | pGMLP000540 | Human CCL11 Lentivirus plasmid |
ORF Viral Vector | pGMAP000414 | Human CCL11 Adenovirus plasmid |
ORF Viral Vector | vGMLP000540 | Human CCL11 Lentivirus particle |
ORF Viral Vector | vGMAP000414 | Human CCL11 Adenovirus particle |
Target information
Target ID | GM-T16888 |
Target Name | CCL11 |
Gene ID | 6356, 574218 |
Gene Symbol and Synonyms | CCL11,Eotaxin,SCYA11 |
Uniprot Accession | P51671 |
Uniprot Entry Name | CCL11_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target, INN Index, Cytokine Target |
Disease | Ovary Cancer |
Gene Ensembl | ENSG00000172156 |
Target Classification | Not Available |
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
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