Human IL19/IL-10C/MDA1 ORF/cDNA clone-Lentivirus plasmid (NM_013371)
Cat. No.: pGMLP-IL-026
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human IL19/IL-10C/MDA1 Lentiviral expression plasmid for IL19 lentivirus packaging, IL19 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product Description
Catalog ID | pGMLP-IL-026 |
Gene Name | IL19 |
Accession Number | NM_013371 |
Gene ID | 29949 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 534 bp |
Gene Alias | IL-10C,MDA1,NG.1,ZMDA1 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T44584-Ab | Anti-IL19/ IL-10C/ MDA1 functional antibody |
Target Antigen | GM-Tg-g-T44584-Ag | IL19 protein |
Cytokine | cks-Tg-g-GM-T44584 | IL19 (IL19) protein & antibody |
ORF Viral Vector | pGMLP004788 | Human IL19 Lentivirus plasmid |
ORF Viral Vector | pGMLP-IL-026 | Human IL19 Lentivirus plasmid |
ORF Viral Vector | pGMAP-IL-109 | Human IL19 Adenovirus plasmid |
ORF Viral Vector | vGMLP004788 | Human IL19 Lentivirus particle |
ORF Viral Vector | vGMLP-IL-026 | Human IL19 Lentivirus particle |
ORF Viral Vector | vGMAP-IL-109 | Human IL19 Adenovirus particle |
Target information
Target ID | GM-T44584 |
Target Name | IL19 |
Gene ID | 29949, 329244, 694806, 681145, 101090582, 490265, 527634, 100055588 |
Gene Symbol and Synonyms | IL-10C,IL19,MDA1,NG.1,ZMDA1 |
Uniprot Accession | Q9UHD0 |
Uniprot Entry Name | IL19_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target, Cytokine Target |
Disease | Not Available |
Gene Ensembl | ENSG00000142224 |
Target Classification | Not Available |
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
About GMVC
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