Promise-ORF™
Click here to discover the largest collection of GeneMedi's Promise-ORF™ ORF/cDNA expression clones
Plasmid quantity:
- 10mg, 50mg, 100mg, 500mg, >1g
Talk to our Expert:
- • Research Grade
- • Endotoxin-Free Grade
- • High Quality (HQ) Grade
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Human PCSK9/FH3/FHCL3 ORF/cDNA clone-Adenovirus plasmid (NM_174936.4)
SKU: pGMAD000996
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human PCSK9/FH3/FHCL3 adenoviral expression plasmid for PCSK9 adenovirus packaging, PCSK9 adenovirus.
Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.
MSDS
Go to
PCSK9/FH3 products
collection>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product Description
| Catalog ID | pGMAD000996 |
| Gene Name | PCSK9 |
| Accession Number | NM_174936.4 |
| Gene ID | 255738 |
| Species | Human |
| Product Type | Adenovirus plasmid (overexpression) |
| Insert Length | 2079 bp |
| Gene Alias | FH3,FHCL3,HCHOLA3,LDLCQ1,NARC-1,NARC1,PC9 |
| Fluorescent Reporter | Null |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Kanamycin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
| Target ID | GM-T62206 |
| Target Name | PCSK9 |
| Gene ID | 255738, 100102, 717147, 298296, 102152231, 100147049 |
| Gene Symbol and Synonyms | FH3,FHCL3,HCHOLA3,LDLCQ1,NARC-1,NARC1,PC9,PCSK9 |
| Uniprot Accession | Q8NBP7 |
| Uniprot Entry Name | PCSK9_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, INN Index |
| Disease | Ovary Cancer |
| Gene Ensembl | ENSG00000169174 |
| Target Classification | Not Available |
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
Facebook
LinkedIn
Twitter
