Human MAVS/CARDIF/IPS-1 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_020746.5)

Cat. No.: pGMAAV000916
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human MAVS/CARDIF/IPS-1 Adeno-associated virus expression plasmid (ITR-vector) for MAVS AAV packaging, MAVS AAV production.The purified Human MAVS/CARDIF/IPS-1 AAV particle serves as an invaluable asset for in-depth in vivo MAVS studies, mechanism of action (MOA) research, and the evolution of MAVS-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000916
Gene Name MAVS
Accession Number NM_020746.5
Gene ID 57506
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1623 bp
Gene Alias CARDIF,IPS-1,IPS1,VISA
Fluorescent Reporter Null
Mammalian Cell Selection Null
Fusion Tag HA (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCGTTTGCTGAAGACAAGACCTATAAGTATATCTGCCGCAATTTCAGCAATTTTTGCAATGTGGATGTTGTAGAGATTCTGCCTTACCTGCCCTGCCTCACAGCAAGAGACCAGGATCGACTGCGGGCCACCTGCACACTCTCAGGGAACCGGGACACCCTCTGGCATCTCTTCAATACCCTTCAGCGGCGGCCCGGCTGGGTGGAGTACTTCATTGCGGCACTGAGGGGCTGTGAGCTAGTTGATCTCGCGGACGAAGTGGCCTCTGTCTACCAGAGCTACCAGCCTCGGACCTCGGACCGTCCCCCAGACCCACTGGAGCCACCGTCACTTCCTGCTGAGAGGCCAGGGCCCCCCACACCTGCTGCGGCCCACAGCATCCCCTACAACAGCTGCAGAGAGAAGGAGCCAAGTTACCCCATGCCTGTCCAGGAGACCCAGGCGCCAGAGTCCCCAGGAGAGAATTCAGAGCAAGCCCTGCAGACGCTCAGCCCCAGAGCCATCCCAAGGAATCCAGATGGTGGCCCCCTGGAGTCCTCCTCTGACCTGGCAGCCCTCAGCCCTCTGACCTCCAGCGGGCATCAGGAGCAGGACACAGAACTGGGCAGTACCCACACAGCAGGTGCGACCTCCAGCCTCACACCATCCCGTGGGCCTGTGTCTCCATCTGTCTCCTTCCAGCCCCTGGCCCGTTCCACCCCCAGGGCAAGCCGCTTGCCTGGACCCACAGGGTCAGTTGTATCTACTGGCACCTCCTTCTCCTCCTCATCCCCTGGCTTGGCCTCTGCAGGGGCTGCAGAGGGTAAACAGGGTGCAGAGAGTGACCAGGCCGAGCCTATCATCTGCTCCAGTGGGGCAGAGGCACCTGCCAACTCTCTGCCCTCCAAAGTGCCTACCACCTTGATGCCTGTGAACACAGTGGCCCTGAAAGTGCCTGCCAACCCAGCATCTGTCAGCACAGTGCCCTCCAAGTTGCCAACTAGCTCAAAGCCCCCTGGTGCAGTGCCTTCTAATGCGCTCACCAATCCAGCACCATCCAAATTGCCCATCAACTCAACCCGTGCTGGCATGGTGCCATCCAAAGTGCCTACTAGCATGGTGCTCACCAAGGTGTCTGCCAGCACAGTCCCCACTGACGGGAGCAGCAGAAATGAGGAGACCCCAGCAGCTCCAACACCCGCCGGCGCCACTGGAGGCAGCTCAGCCTGGCTAGACAGCAGCTCTGAGAATAGGGGCCTTGGGTCGGAGCTGAGTAAGCCTGGCGTGCTGGCATCCCAGGTAGACAGCCCGTTCTCGGGCTGCTTCGAGGATCTTGCCATCAGTGCCAGCACCTCCTTGGGCATGGGGCCCTGCCATGGCCCAGAGGAGAATGAGTATAAGTCCGAGGGCACCTTTGGGATCCACGTGGCTGAGAACCCCAGCATCCAGCTCCTGGAGGGCAACCCTGGGCCACCTGCGGACCCGGATGGCGGCCCCAGGCCACAAGCCGACCGGAAGTTCCAGGAGAGGGAGGTGCCATGCCACAGGCCCTCACCTGGGGCTCTGTGGCTCCAGGTGGCTGTGACAGGGGTGCTGGTAGTCACACTCCTGGTGGTGCTGTACCGGCGGCGTCTGCACTAG
ORF Protein Sequence MPFAEDKTYKYICRNFSNFCNVDVVEILPYLPCLTARDQDRLRATCTLSGNRDTLWHLFNTLQRRPGWVEYFIAALRGCELVDLADEVASVYQSYQPRTSDRPPDPLEPPSLPAERPGPPTPAAAHSIPYNSCREKEPSYPMPVQETQAPESPGENSEQALQTLSPRAIPRNPDGGPLESSSDLAALSPLTSSGHQEQDTELGSTHTAGATSSLTPSRGPVSPSVSFQPLARSTPRASRLPGPTGSVVSTGTSFSSSSPGLASAGAAEGKQGAESDQAEPIICSSGAEAPANSLPSKVPTTLMPVNTVALKVPANPASVSTVPSKLPTSSKPPGAVPSNALTNPAPSKLPINSTRAGMVPSKVPTSMVLTKVSASTVPTDGSSRNEETPAAPTPAGATGGSSAWLDSSSENRGLGSELSKPGVLASQVDSPFSGCFEDLAISASTSLGMGPCHGPEENEYKSEGTFGIHVAENPSIQLLEGNPGPPADPDGGPRPQADRKFQEREVPCHRPSPGALWLQVAVTGVLVVTLLVVLYRRRLH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP1153-Ab Anti-MAVS monoclonal antibody
    Target Antigen GM-Tg-g-IP1153-Ag MAVS protein
    ORF Viral Vector pGMLP001134 Human MAVS Lentivirus plasmid
    ORF Viral Vector pGMLV001857 Human MAVS Lentivirus plasmid
    ORF Viral Vector pGMAAV000910 Human MAVS Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV000916 Human MAVS Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC000821 Human MAVS Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001134 Human MAVS Lentivirus particle
    ORF Viral Vector vGMLV001857 Human MAVS Lentivirus particle
    ORF Viral Vector vGMAAV000910 Human MAVS Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV000916 Human MAVS Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-IP1153
    Target Name MAVS
    Gene ID 57506, 228607, 717616, 311430, 101085709, 485789, 618508, 100066212
    Gene Symbol and Synonyms CARDIF,D430028G21Rik,IPS-1,IPS1,MAVS,VISA
    Uniprot Accession Q7Z434
    Uniprot Entry Name MAVS_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000088888
    Target Classification Not Available

    This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity. [provided by RefSeq, Jul 2020]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.