SAA (Serum Amyloid A) in Veterinary Diseases: A Critical Diagnostic Tool

This is an acute phase protein and is elevated during inflammation or infection of the body system. Thus, increased SAA level is beneficial for detecting infection, chronic inflammation, tissue damage.


Product list of GeneMedi's SAA(Serum Amyloid A) products


Catalog No. Products Name Detected Species Products Information
GMP-BOV-Serum-amyloid-A-Ag Bovine Serum amyloid A Bovines/Cattle Details
GMP-BOV-Serum-amyloid-A-Ab Anti-bovine SAA protein  monoclonal antibody (mAb) Bovines/Cattle Details
GMP-CAN-Serum-amyloid-A-Ab Anti-Canine Serum amyloid A  monoclonal antibody (mAb) Dog/Canine Details
GMP-CAN-Serum-amyloid-A-Ag Serum amyloid A Dog/Canine Details
GMP-EQU-Serum-amyloid-A-Ab Anti-Equine SAA  monoclonal antibody (mAb) Equine/Horse Details
GMP-EQU-Serum-amyloid-A-Ag Serum amyloid A Equine/Horse Details
GMP-FEL-Serum-amyloid-A-Ab Anti-Feline Serum amyloid A  monoclonal antibody (mAb) Cat/Feline Details
GMP-FEL-Serum-amyloid-A-Ag Serum amyloid A Cat/Feline Details


Understanding SAA: A Marker of Inflammation in Pets

Serum Amyloid A (SAA) which respond to Synonym inflammation, infection, trauma, or stress in animals by raising to a significantly high level. This protein is synthesized mainly in the liver and is used as an indicator for diagnosing acute inflammation in various animals such as horse, dogs, cat, and cattle.

SAA (Serum Amyloid A)



The Role of SAA in Identifying Diseases Across Animal Species

SAA production increases rapidly within hours of an inflammatory event and decreases almost as swiftly in response to inflammation resolution, which makes the concept of SAA levels a very specific and dynamic one in relation to acute changes in an animal’s health condition.Due to its rapid response to inflammatory stimuli, SAA is particularly useful for:
(1) Early diagnosis hence points to the detection of diseases and infections before clinical signs manifest themselves.
(2) SAA levels may be used for assessing the advancement of the diseases or the efficacy of treatments as changes in concentrations can be indicative of the therapy session results.
(3) Evaluating surgical recovery and identification of other situations that may trigger inflammation after surgery.

In veterinary practice, measuring SAA levels can aid in the diagnosis and management of various conditions, including:In veterinary practice, measuring SAA levels can aid in the diagnosis and management of various conditions, including:
(1) Infections, parasitic and those caused by bacteria and viruses.
(2) Arthritis- condition affiliated with inflammation.
(3) Lastly, there are certain diseases that induce worldwide inflammation such as sepsis.

CONCLUSION: SAA analysis is normally done through blood sample tests and the tests used are specific immunoassays of animal species. Due to SAA involvement in the acute phase, the role of this protein has been useful in the diagnosis of the presence and severity of inflammation in animals and the consequential management of the disease as identified from the test results.

Serum Amyloid A (SAA) as a Biomarker for Inflammatory Diseases in Animals
Animals Normal Range Possible Diseases Listed Specimens/Biofluids Measurement Method
Cat <10 µg/mL Infections, Inflammatory Diseases, Neoplasia, Trauma Blood Immunoassay
Dog <10 µg/mL Infections, Inflammatory Diseases, Neoplasia, Trauma, Autoimmune Disorders Blood Immunoassay
Horse <20 µg/mL Infections, Inflammatory Bowel Disease, Respiratory Diseases, Post-surgical Inflammation Blood Immunoassay
Cattle <20 µg/mL Mastitis, Metritis, Respiratory Infections, Septicemia Blood Immunoassay





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