SAA (Serum Amyloid A) in Veterinary Diseases: A Critical Diagnostic Tool

This is an acute phase protein and is elevated during inflammation or infection of the body system. Thus, increased SAA level is beneficial for detecting infection, chronic inflammation, tissue damage.

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Product list of GeneMedi's SAA(Serum Amyloid A) products

Catalog No.	Products Name	Detected Species	Products Information
GMP-BOV-Serum-amyloid-A-Ag	Bovine Serum amyloid A	Bovines/Cattle	Details
GMP-BOV-Serum-amyloid-A-Ab	Anti-bovine SAA protein  monoclonal antibody (mAb)	Bovines/Cattle	Details
GMP-CAN-Serum-amyloid-A-Ab	Anti-Canine Serum amyloid A  monoclonal antibody (mAb)	Dog/Canine	Details
GMP-CAN-Serum-amyloid-A-Ag	Serum amyloid A	Dog/Canine	Details
GMP-EQU-Serum-amyloid-A-Ab	Anti-Equine SAA  monoclonal antibody (mAb)	Equine/Horse	Details
GMP-EQU-Serum-amyloid-A-Ag	Serum amyloid A	Equine/Horse	Details
GMP-FEL-Serum-amyloid-A-Ab	Anti-Feline Serum amyloid A  monoclonal antibody (mAb)	Cat/Feline	Details
GMP-FEL-Serum-amyloid-A-Ag	Serum amyloid A	Cat/Feline	Details

Understanding SAA: A Marker of Inflammation in Pets

The Role of SAA in Identifying Diseases Across Animal Species

SAA production increases rapidly within hours of an inflammatory event and decreases almost as swiftly in response to inflammation resolution, which makes the concept of SAA levels a very specific and dynamic one in relation to acute changes in an animal’s health condition.Due to its rapid response to inflammatory stimuli, SAA is particularly useful for:
(1) Early diagnosis hence points to the detection of diseases and infections before clinical signs manifest themselves.
(2) SAA levels may be used for assessing the advancement of the diseases or the efficacy of treatments as changes in concentrations can be indicative of the therapy session results.
(3) Evaluating surgical recovery and identification of other situations that may trigger inflammation after surgery.

In veterinary practice, measuring SAA levels can aid in the diagnosis and management of various conditions, including:In veterinary practice, measuring SAA levels can aid in the diagnosis and management of various conditions, including:
(1) Infections, parasitic and those caused by bacteria and viruses.
(2) Arthritis- condition affiliated with inflammation.
(3) Lastly, there are certain diseases that induce worldwide inflammation such as sepsis.

CONCLUSION: SAA analysis is normally done through blood sample tests and the tests used are specific immunoassays of animal species. Due to SAA involvement in the acute phase, the role of this protein has been useful in the diagnosis of the presence and severity of inflammation in animals and the consequential management of the disease as identified from the test results.

Serum Amyloid A (SAA) as a Biomarker for Inflammatory Diseases in Animals

Animals	Normal Range	Possible Diseases Listed	Specimens/Biofluids	Measurement Method
Cat	<10 µg/mL	Infections, Inflammatory Diseases, Neoplasia, Trauma	Blood	Immunoassay
Dog	<10 µg/mL	Infections, Inflammatory Diseases, Neoplasia, Trauma, Autoimmune Disorders	Blood	Immunoassay
Horse	<20 µg/mL	Infections, Inflammatory Bowel Disease, Respiratory Diseases, Post-surgical Inflammation	Blood	Immunoassay
Cattle	<20 µg/mL	Mastitis, Metritis, Respiratory Infections, Septicemia	Blood	Immunoassay