Pancreatitis in Animals: Detecting the Signs and Biomarkers
Pancreatitis is the inflammation of the pancreas and this is usually as a result of gallstones or excessive use of alcohol. This results to abdoominal pain, nausea and vomiting of intense nature. Diagnosis is facilitated by a biomarker known as pancreatic Lipase since its level increases in the blood when there is damage to pancreatic cells, so for pancreatitis. The management includes medication regarding the pain and giving him fluids, in some occasions he might require surgery.
| GMP-BOV-pancreatic-lipase-Ag | pancreatic lipase | Bovines/Cattle | Details |
| GMP-BOV-pancreatic-lipase-Ab | Anti-Bovine pancreatic lipase mouse monoclonal antibody (mAb) | Bovines/Cattle | Details |
| GMP-CAN-Pancreatic-lipase-Ag | Canine pancreatic lipase | Dog/Canine | Details |
| GMP-CAN-Pancreatic-lipase-Ab | Anti-Canine pancreatic lipase mouse monoclonal antibody (mAb) | Dog/Canine | Details |
| GMP-EQU-pancreatic-lipase-Ag | pancreatic lipase | Equine/Horse | Details |
| GMP-EQU-pancreatic-lipase-Ab | Anti-Equine pancreatic lipase mouse monoclonal antibody (mAb) | Equine/Horse | Details |
| GMP-FEL-Pancreatic-lipase-Ag | feline pancreatic lipase | Cat/Feline | Details |
| GMP-FEL-Pancreatic-lipase-Ab | Anti-feline pancreatic lipase mouse monoclonal antibody (mAb) | Cat/Feline | Details |
Understanding Pancreatitis in Pets: Symptoms and Causes
Animal pancreatitis is a disease which involves inflammation of the pancreas that consequently results to a number of gastrointestinal and systemic manifestations. The symptoms are usually vomiting, abdominal pain, best all indication, and tiredness. There is acute and chronic forms of the disease and as can be inferred acute is more severe in its presentation. The disease is known to be widespread in different animals that humans associate with pets and can be as diverse as dogs, cats, horses, and cattle but mostly, cats and dogs are the most affected.
Key Biomarkers for Diagnosing Pancreatitis in Dogs and Cats
This table outlines critical biomarkers like SAA, CRP, and NT-proBNP, their normal ranges, and implications in diseases for dogs and cats. It serves as a reference for veterinarians to assess inflammation, infection, and cardiac health, incorporating measurement methods and age considerations.
| Biomarker | Normal Range | Implications in Disease | Specimens/Biofluids | Age Considerations | Measurement Method |
|---|---|---|---|---|---|
| D-Dimer | Dog: 0-0.5 µg/mL; Cat: 0-0.5 µg/mL |
Increased in DIC, thromboembolism | Blood, Plasma | Older animals may have higher levels | Immunoassay |
| Lipase | Dog: 10-200 U/L; Cat: 10-200 U/L |
Elevated in pancreatitis | Serum, Blood | Levels may increase with age | Enzymatic assay |
| Amylase | Dog: 500-1500 U/L; Cat: 100-1200 U/L |
Elevated in pancreatitis, kidney disease | Serum, Blood | No specific age correlation | Enzymatic assay |
| cPLI (canine Pancreatic Lipase Immunoreactivity) | <200 µg/L | Specific for canine pancreatitis | Serum, Blood | Not applicable | Immunoassay |
| fPLI (feline Pancreatic Lipase Immunoreactivity) | <5.3 µg/L | Specific for feline pancreatitis | Serum, Blood | Not applicable | Immunoassay |
| CRP (C-Reactive Protein) | Dog: <10 mg/L; Cat: Typically low/undetectable |
General inflammation marker, can be elevated in pancreatitis | Serum, Blood | May vary with age; older pets may have slightly higher levels | Immunoassay |
| SAA (Serum Amyloid A) | Variable | Acute phase protein, elevated in inflammation including pancreatitis | Blood | Levels can increase with age | Immunoassay |
| ALT (Alanine Aminotransferase) | Dog: 10-125 U/L; Cat: 10-100 U/L |
Liver enzyme that may increase with pancreatitis | Serum, Blood | Younger animals may have slightly higher levels due to growth | Biochemical assay |
| BUN (Blood Urea Nitrogen) | Dog: 7-27 mg/dL; Cat: 16-36 mg/dL |
Elevated in kidney disease, dehydration | Blood, Serum | Older pets may show higher levels due to decreased kidney function | Biochemical assay |
| Glucose | Dog: 70-150 mg/dL; Cat: 70-150 mg/dL |
Hyperglycemia can occur in pancreatitis | Blood, Serum | Stress can elevate levels, especially in cats | Biochemical assay |
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