Immuno-Diagnostics Antibodies & Antigens for Veterinary Kidney Function Test
Kidney function is essentially necessary in animals to remove blood wastes, excess water and
electrolytes and other related roles in controlling blood pressure. Kidneys also release
erythropoietin for the formation of required red blood cells and hormone to balance acid and base
concentration to make proper functioning of nerve and muscle.
GeneMedi's Product list for
Veterinary Kidnye Function Test products
Kidney function in animals is one of the significant body functions, which are necessary for the
well-being of an animal and the performance of numerous tasks. Kidneys help in filtering the blood ,
removing wastes products and substances that may be in excess in the body in maintaining the balance
of body fluids. It manages water and electrolytes, the concentrations of salts and acids in the body
necessary for proper function of the nervous and muscular systems. Kidneys also interact with the
regulation of blood pressure through affecting blood volume and releasing an enzyme called renin.
Besides, they synthesise erythropoietin which helps the bones produce red blood cells that aid in
circulation of oxygen in the body. Thus, maintaining the acid-base equilibrium, the kidneys have a
central role in the general metabolism.
Detecting Diseases Through Kidney function in Animals
This table may be employed by veterinarians and other health care professionals involved in the
evaluation of kidney and other organs’ function in animals and developing diagnosis and management
plans of the disease based on these biomarkers.
Biomarker
Animals
Normal Range
Implications in Disease
Specimens/Biofluids
Age Considerations
Measurement Method
Creatinine
Dogs, Cats
0.5-1.6 mg/dL
High in renal damage or failure, low may indicate reduced muscle mass
Blood
Lower in older animals
Jaffe method
Blood Urea Nitrogen (BUN)
Dogs, Cats
10-30 mg/dL
High in renal failure, dehydration; low in liver disease
Blood
Higher in older animals
Enzymatic colorimetric assay
Phosphate
Dogs, Cats
2.5-6.0 mg/dL
High in chronic kidney disease, low in malabsorption
Blood
Younger animals higher
Colorimetric assay
Albumin
Dogs, Cats
2.5-4.0 g/dL
Low in kidney disease (protein-losing nephropathy)
Blood
Varies with disease state
Bromocresol green method
Sodium
Dogs, Cats
139-154 mEq/L
Low in kidney disease, can also be high depending on hydration status
Blood
Not age-dependent
Ion-selective electrode
Potassium
Dogs, Cats
3.5-5.8 mEq/L
High in acute kidney failure, low in chronic kidney disease or poor intake
Blood
Not age-dependent
Ion-selective electrode
Calcium
Dogs, Cats
8.8-11.3 mg/dL
High or low in kidney disease depending on stage and secondary conditions
Blood
Varies with breed/age
Colorimetric assay
Urine Specific Gravity
Dogs, Cats
1.015-1.045
Low in kidney disease (impaired concentrating ability)
Urine
Higher in young animals
Refractometer
Urine Protein
Dogs, Cats
Ratio <0.5
High in kidney disease (protein-losing nephropathy)
Urine
Not age-dependent
Protein-to-creatinine ratio test
Parathyroid Hormone (PTH)
Dogs, Cats
10-65 pg/mL
High in chronic kidney disease due to phosphorus retention