D-Dimer Antibodies & Antigens for Veterinary Diagnostics
D-Dimer is a soluble fibrin which reveals coagulation and thrombosis faculties in animals. It shows that Anti-D-Dimer antibodies are applied in veterinary medicine for blood clotting analysis in order to diagnose DIC and deep vein thrombosis, which is of great significance to animal health and preventing severe coagulation diseases.
| Catalog No. | Products Name | Detected Species | Disease/Condition | Products Type | Products Information |
| GMP-FEL-D-Dimer-Ag | Feline D dimer (D-Dimer) antigen | Cat/Feline | Thrombosis, disseminated intravascular coagulation (DIC) | peptide-(naked/BSA/OVA) | Details |
| GMP-FEL-D-Dimer-Ab | Anti-Feline D dimer (D-Dimer) antibody | Cat/Feline | Thrombosis, disseminated intravascular coagulation (DIC) | antibody(Fc/mFc) | Details |
| GMP-CAN-D-Dimer-Ag | Canine D dimer (D-Dimer) antigen | Dog/Canine | Thrombosis, disseminated intravascular coagulation (DIC) | peptide-(naked/BSA/OVA) | Details |
| GMP-CAN-D-Dimer-Ab | Anti-Canine D dimer (D-Dimer) antibody | Dog/Canine | Thrombosis, disseminated intravascular coagulation (DIC) | antibody(Fc/mFc) | Details |
| GMP-BOV-D-Dimer-Ag | Bovine D dimer (D-Dimer) antigen | Bovines/Cattle | Deep vein thrombosis (DVT) | peptide-(naked/BSA/OVA) | Details |
| GMP-BOV-D-Dimer-Ab | Anti-Bovine D dimer (D-Dimer) antibody | Bovines/Cattle | Deep vein thrombosis (DVT) | antibody(Fc/mFc) | Details |
| GMP-EQU-D-Dimer-Ag | Equine D dimer (D-Dimer) antigen | Equine/Horse | Thrombosis, disseminated intravascular coagulation (DIC) | peptide-(naked/BSA/OVA) | Details |
| GMP-EQU-D-Dimer-Ab | Anti-Equine D dimer (D-Dimer) antibody | Equine/Horse | Thrombosis, disseminated intravascular coagulation (DIC) | antibody(Fc/mFc) | Details |
Understanding D-Dimer: Its Role and Significance in Animals
D-Dimer is the reduced product of blood fibrin that circulates in the blood stream after the clot has been dissolved by fibrinolysis. It is a degradation product of Fibrin, which is a building block of the blood clots generally referred to as a clot. Like for human patients, the degrees of D-Dimer in animals are accrued in an attempt to help determine if there is an active clotting and clot breakdown process actually going on in the body.
D-Dimer
Detecting Thrombotic Disorders: How D-Dimer Helps Identify Veterinary Diseases
In veterinary medicine, elevated D-Dimer levels can indicate various conditions related to abnormal clotting or thrombosis, including:In veterinary medicine, elevated D-Dimer levels can indicate various conditions related to abnormal clotting or thrombosis, including:
· Disseminated Intravascular Coagulation (DIC): A critical illness wherein there is formation of clots in different organs, use up of clotting factors and platelets, therefore causing hemorrhage.
· Deep Vein Thrombosis (DVT): It is a formation of a blood clot in the deep vein, which if travels up to the lungs may be dangerous to the client’s life due to pulmonary embolism.
· Pulmonary Embolism (PE): A clot or plug in one of the pulmonary artery which is in the lungs commonly originated from the legs and other parts of the body.
· Other Thromboembolic Diseases: Situation that develops and causes possibly leads to blockage of circulation in the body, for instance in the heart; causes heart attack or in the brain; causes stroke.
The test for D-Dimer in animals is highly appropriate in the emergency and critical care as early and correct diagnosis of these conditions can be very much of essence. However, it is necessary to state that, although the increase in D-Dimer level indicates the existence of thromboembolic diseases, it does not indicate the location or cause of the thrombi. D-Dimer has been also increased in the conditions that are not necessary associated with clotting disorders but are associated with inflammation, cancer, and some infectious diseases; thus, results need to be considered in conjunction with clinical signs and other diagnostic results.
Such a test has to be used together with other methods because the D-Dimer levels may be affected by other factors indicating that a veterinarian may rely on this test to look at an animal’s overall health and treatment plan.
| Animals | Possible Diseases Listed | Specimens/Biofluids | Measurement Method |
|---|---|---|---|
| Dog | Disseminated Intravascular Coagulation (DIC), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Heartworm Disease, Cancer, Traumatic injuries, Surgery-related thrombosis, Immune-mediated hemolytic anemia (IMHA), Sepsis, Liver disease | Blood | Immunoassay |
| Cat | Arterial Thromboembolism (ATE), Disseminated Intravascular Coagulation (DIC), Heartworm Disease, Cancer, Traumatic injuries, Surgery-related thrombosis, Pancreatitis, Sepsis, Liver disease, Feline Infectious Peritonitis (FIP) | Blood | Immunoassay |
| Horse | Disseminated Intravascular Coagulation (DIC), Colic with thrombosis, Laminitis, Post-surgical Thromboembolism, Septicemia, Liver disease, Neonatal isoerythrolysis, Pneumonia leading to PE, Traumatic injuries, Immune-mediated diseases | Blood | Immunoassay |
| Cattle | Disseminated Intravascular Coagulation (DIC), Thromboembolic pneumonia, Hardware disease with thrombosis, Postparturient Hemorrhagic Syndrome (PPHS), Septicemia, Liver disease, Traumatic injuries, Surgery-related thrombosis, Mastitis with sepsis, Metritis with sepsis | Blood | Immunoassay |
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