Immuno-Diagnostics Antibodies & Antigens for Veterinary Coagulation Test
Coagulation on the other hand is the process of putting a halt on blood loss through proper clotting of blood. FDP or D-dimer is crucial for the identification of clots and their degradation in numerous critical diseases. Abnormal results include an increased risk for thrombosis or disseminated intravascular coagulation pending diagnosis and treatment in veterinary medicine.
| Catalog No. | Products Name | Detected Species | Disease/Condition | Products Type | Products Information |
| GMP-FEL-D-Dimer-Ag | Feline D dimer (D-Dimer) antigen | Cat/Feline | Thrombosis, disseminated intravascular coagulation (DIC) | peptide-(naked/BSA/OVA) | Details |
| GMP-FEL-D-Dimer-Ab | Anti-Feline D dimer (D-Dimer) antibody | Cat/Feline | Thrombosis, disseminated intravascular coagulation (DIC) | antibody(Fc/mFc) | Details |
| GMP-CAN-D-Dimer-Ag | Canine D dimer (D-Dimer) antigen | Dog/Canine | Thrombosis, disseminated intravascular coagulation (DIC) | peptide-(naked/BSA/OVA) | Details |
| GMP-CAN-D-Dimer-Ab | Anti-Canine D dimer (D-Dimer) antibody | Dog/Canine | Thrombosis, disseminated intravascular coagulation (DIC) | antibody(Fc/mFc) | Details |
| GMP-BOV-D-Dimer-Ag | Bovine D dimer (D-Dimer) antigen | Bovines/Cattle | Deep vein thrombosis (DVT) | peptide-(naked/BSA/OVA) | Details |
| GMP-BOV-D-Dimer-Ab | Anti-Bovine D dimer (D-Dimer) antibody | Bovines/Cattle | Deep vein thrombosis (DVT) | antibody(Fc/mFc) | Details |
| GMP-EQU-D-Dimer-Ag | Equine D dimer (D-Dimer) antigen | Equine/Horse | Thrombosis, disseminated intravascular coagulation (DIC) | peptide-(naked/BSA/OVA) | Details |
| GMP-EQU-D-Dimer-Ab | Anti-Equine D dimer (D-Dimer) antibody | Equine/Horse | Thrombosis, disseminated intravascular coagulation (DIC) | antibody(Fc/mFc) | Details |
Understanding Coagulation: Key Biomarkers in Veterinary Health
Haemostasis in animals implies the process of blood clotting to provide for cessation of bleeding. It is a multiple series of processes where several proteins dissolved in the blood termed as coagulation factors trigger their specific actions. Blood clotting is crucial especially when a person has an injury or a surgery, so that he does not lose a lot of blood. However, disorders in process may also result in either formation of a clot, thrombosis, or the lack of clot formation, hemorrhage which may be fatal.
Diagnosing and Managing Coagulation Disorders in Pets
These antecedents give blood clotting a connotation of haemostasis in animals that indicate the need for a stoppage of blood flow. It is a multiple series of processes in which, several proteins dissolved in the blood called the coagulation factors bring out their respective actions. Coagulation is very important especially when for example a person has a cut or undergoes surgery so that he or she does not lose much blood. However, disorders in process may either lead to the formation of a clot, arising to thrombosis or lack of it, known as hemorrhage which could possibly be fatal.
| Biomarker | Normal Range | Implications in Disease | Specimens/Biofluids | Age Considerations | Measurement Method |
|---|---|---|---|---|---|
| D-Dimer | Variable; species-dependent | Elevated in thrombosis, DIC | Blood, Plasma | May vary with age; older animals may have higher baseline levels | Immunoassay |
| PT (Prothrombin Time) | Variable; species-dependent | Prolonged in coagulation factor deficiency, liver disease | Blood | No specific age correlation | Coagulometer |
| aPTT (Activated Partial Thromboplastin Time) | Variable; species-dependent | Prolonged in intrinsic pathway factor deficiencies | Blood | No specific age correlation | Coagulometer |
| Fibrinogen | Variable; species-dependent | Elevated in inflammation, decreased in severe DIC | Blood | Levels can increase with inflammation | Heat precipitation, Coagulometer |
| Platelet Count | Variable; species-dependent | Decreased in thrombocytopenia, increased in thrombocytosis | Blood | Young animals may have higher counts | Automated Hematology Analyzer |
| vWF (von Willebrand Factor) | Variable; species-dependent | Decreased in von Willebrand disease | Blood, Plasma | Breed-specific variations | ELISA, Immunoassay |
| AT (Antithrombin) | Variable; species-dependent | Decreased in DIC, liver disease | Blood, Plasma | No specific age correlation | Immunoassay |
| Factor VIII | Variable; species-dependent | Decreased in Hemophilia A | Blood, Plasma | Genetic predisposition | Coagulometer, Immunoassay |
| Thrombin Time | Variable; species-dependent | Prolonged in fibrinogen deficiency or dysfunction | Blood | No specific age correlation | Coagulometer |
| ACT (Activated Clotting Time) | Variable; species-dependent | Prolonged in coagulation factor deficiencies, anticoagulant therapy | Blood | No specific age correlation | Coagulometer |
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