cTnI (Cardiac Troponin I) in Veterinary Diseases: A Vital Diagnostic Tool

cTnI (Cardiac Troponin I), is an antigenic protein present only in cardiac muscle tissue. It acts as a cardiac troponin that is cardiac injury biomarker in human and veterinary practice because it is used in the diagnosis of myocardial infarction, heart failure, and cardiomyopathies.


Product list of GeneMedi's cTnI (Cardiac Troponin I) products


Catalog No. Products Name Detected Species Products Information
GMP-BOV-cTnI-Ag cTnI Bovines/Cattle Details
GMP-BOV-cTnI-Ab Anti-Bovine cTnl monoclonal antibody (mAb) Bovines/Cattle Details
GMP-CAN-cTnI-Ag cTnI Dog/Canine Details
GMP-CAN-cTnI-Ab Anti-Canine cTnl monoclonal antibody (mAb) Dog/Canine Details
GMP-EQU-cTnI-Ag cTnI Equine/Horse Details
GMP-EQU-cTnI-Ab Anti-Equine cTnl monoclonal antibody (mAb) Equine/Horse Details
GMP-FEL-cTnI-Ag cTnI Cat/Feline Details
GMP-FEL-cTnI-Ab Anti-Feline cTnl monoclonal antibody (mAb) Cat/Feline Details


Decoding cTnI: The Essential Heart Health Marker for Pets

Cardiac Troponin I (cTnI) is a protein which is expressed on cardiac muscles’ cell and is an active participle in muscle contraction. As for veterinary medicine, it is significant to state that cTnI is considered as a specific and sensitive biomarker for confirming the presence of Myocardial, aka cardiac muscle, injury in numerous animal species, such as dogs, cats, horses and others.

Structure of cTnl.



Navigating Cardiac Conditions: Diseases Identified Through cTnI in Animals

When heart muscle cells sustain damage, cardiac troponin I (cTnI) is released into the bloodstream, serving as a valuable diagnostic tool for evaluating cardiac health. Elevated levels of cTnI in the blood indicate myocardial damage, which can stem from various cardiac conditions such as myocardial infarction (heart attack), myocarditis (heart muscle inflammation), cardiomyopathy (heart muscle disease affecting size, shape, and structure), direct heart injury due to trauma, or systemic diseases impacting the heart indirectly.

The significance of measuring cTnI extends beyond diagnosing cardiac conditions; it also aids in prognostic assessments, enabling veterinarians to predict the potential outcome of cardiac injury and guide treatment decisions. Research has demonstrated a correlation between elevated cTnI levels and the severity of heart disease in dogs and cats, facilitating the management of conditions like congestive heart failure.

In clinical practice, cTnI levels are typically assessed through blood tests utilizing immunoassay techniques tailored for sensitivity to this specific cardiac biomarker. Due to its specificity for cardiac tissue, cTnI offers a more direct indication of heart muscle damage compared to other nonspecific markers of injury or stress, rendering it a critical component of veterinary diagnostics for pets suspected of having heart disease.

Cardiac Troponin I (cTnI) as a Biomarker for Heart Diseases in Veterinary Medicine
Animals Normal Range Possible Diseases Listed Specimens/Biofluids Measurement Method
Dog <0.1 ng/mL Dilated cardiomyopathy, Myocarditis, Congestive heart failure, Myocardial infarction (rare in dogs), Trauma to the chest, Hypertrophic cardiomyopathy, Systemic hypertension, Pulmonary hypertension, Arrhythmias, Sepsis-induced myocardial damage Blood Immunoassay
Cat <0.1 ng/mL Hypertrophic cardiomyopathy, Myocarditis, Arterial thromboembolism, Congestive heart failure, Hyperthyroidism with secondary heart effects, Systemic hypertension, Pulmonary hypertension, Sepsis-induced myocardial damage, Trauma to the chest, Arrhythmias Blood Immunoassay
Horse - Atrial fibrillation, Myocarditis, Exercise-induced myocardial damage, Congestive heart failure, Trauma to the chest, Systemic infections affecting the heart, Valvular heart disease, Pulmonary hypertension, Arrhythmias, Sepsis-induced myocardial damage Blood Immunoassay
Cattle - Myocarditis, Traumatic reticuloperitonitis (hardware disease) with cardiac involvement, Congestive heart failure, Sepsis-induced myocardial damage, Systemic infections affecting the heart, Pulmonary hypertension, Arrhythmias, Valvular heart disease Blood Immunoassay





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