cTnI (Cardiac Troponin I) in Veterinary Diseases: A Vital Diagnostic Tool

cTnI (Cardiac Troponin I), is an antigenic protein present only in cardiac muscle tissue. It acts as a cardiac troponin that is cardiac injury biomarker in human and veterinary practice because it is used in the diagnosis of myocardial infarction, heart failure, and cardiomyopathies.

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Product list of GeneMedi's cTnI (Cardiac Troponin I) products

Catalog No.	Products Name	Detected Species	Products Information
GMP-BOV-cTnI-Ag	cTnI	Bovines/Cattle	Details
GMP-BOV-cTnI-Ab	Anti-Bovine cTnl monoclonal antibody (mAb)	Bovines/Cattle	Details
GMP-CAN-cTnI-Ag	cTnI	Dog/Canine	Details
GMP-CAN-cTnI-Ab	Anti-Canine cTnl monoclonal antibody (mAb)	Dog/Canine	Details
GMP-EQU-cTnI-Ag	cTnI	Equine/Horse	Details
GMP-EQU-cTnI-Ab	Anti-Equine cTnl monoclonal antibody (mAb)	Equine/Horse	Details
GMP-FEL-cTnI-Ag	cTnI	Cat/Feline	Details
GMP-FEL-cTnI-Ab	Anti-Feline cTnl monoclonal antibody (mAb)	Cat/Feline	Details

Decoding cTnI: The Essential Heart Health Marker for Pets

Navigating Cardiac Conditions: Diseases Identified Through cTnI in Animals

When heart muscle cells sustain damage, cardiac troponin I (cTnI) is released into the bloodstream, serving as a valuable diagnostic tool for evaluating cardiac health. Elevated levels of cTnI in the blood indicate myocardial damage, which can stem from various cardiac conditions such as myocardial infarction (heart attack), myocarditis (heart muscle inflammation), cardiomyopathy (heart muscle disease affecting size, shape, and structure), direct heart injury due to trauma, or systemic diseases impacting the heart indirectly.

The significance of measuring cTnI extends beyond diagnosing cardiac conditions; it also aids in prognostic assessments, enabling veterinarians to predict the potential outcome of cardiac injury and guide treatment decisions. Research has demonstrated a correlation between elevated cTnI levels and the severity of heart disease in dogs and cats, facilitating the management of conditions like congestive heart failure.

In clinical practice, cTnI levels are typically assessed through blood tests utilizing immunoassay techniques tailored for sensitivity to this specific cardiac biomarker. Due to its specificity for cardiac tissue, cTnI offers a more direct indication of heart muscle damage compared to other nonspecific markers of injury or stress, rendering it a critical component of veterinary diagnostics for pets suspected of having heart disease.

Cardiac Troponin I (cTnI) as a Biomarker for Heart Diseases in Veterinary Medicine

Animals	Normal Range	Possible Diseases Listed	Specimens/Biofluids	Measurement Method
Dog	<0.1 ng/mL	Dilated cardiomyopathy, Myocarditis, Congestive heart failure, Myocardial infarction (rare in dogs), Trauma to the chest, Hypertrophic cardiomyopathy, Systemic hypertension, Pulmonary hypertension, Arrhythmias, Sepsis-induced myocardial damage	Blood	Immunoassay
Cat	<0.1 ng/mL	Hypertrophic cardiomyopathy, Myocarditis, Arterial thromboembolism, Congestive heart failure, Hyperthyroidism with secondary heart effects, Systemic hypertension, Pulmonary hypertension, Sepsis-induced myocardial damage, Trauma to the chest, Arrhythmias	Blood	Immunoassay
Horse	-	Atrial fibrillation, Myocarditis, Exercise-induced myocardial damage, Congestive heart failure, Trauma to the chest, Systemic infections affecting the heart, Valvular heart disease, Pulmonary hypertension, Arrhythmias, Sepsis-induced myocardial damage	Blood	Immunoassay
Cattle	-	Myocarditis, Traumatic reticuloperitonitis (hardware disease) with cardiac involvement, Congestive heart failure, Sepsis-induced myocardial damage, Systemic infections affecting the heart, Pulmonary hypertension, Arrhythmias, Valvular heart disease	Blood	Immunoassay