100 Hot Targets Spotlighted | TarMart™-Insight

"100 Hot Targets Spotlighted | TarMart™-Insight" presents a curated list of 100 pivotal targets in biology. Encompassing proteins, genes, and cellular structures, these targets hold significant promise in drug development, therapeutic research, and biotechnological applications. Carefully selected and rigorously analyzed, each target represents a potential opportunity for advancement in its respective field.

The table is continuously updated to ensure it reflects the latest hot targets.
The data from our first edition: TarMart™-Insight: 100 Potential Hot Targets , last refreshed in August 2023.
The data from our third edition: 100 Hot Targets in Focus in 2024 | TarMart™-Insight , last refreshed in March 2024.

Target ID

Target

Uniprot Accession

Disease

Publication link

Target Detail

GM-IP0001

ERN1

O75460

Oncogenic KRAS Resistance

Science

Detail

GM-IP0075

NPR3

P17342

Cardiac Fibrosis

Science Advances

Detail

GM-IP0248

IDH2

P48735

Antitumor Immunity

Science

Detail

GM-IP0354

ARMC10

Q8N2F6

Nerve Regeneration /Immune Regulation

Translational Medicine

Detail

GM-IP1246

NDRG2

Q9UN36

Wound Healing

Nature Communications

Detail

GM-MP0465

FZD6

O60353

Lung Regeneration

Cell

Detail

GM-MP0503

ADGRA2

Q96PE1

Lung Cancer Brain Metastases

Cancer Cell

Detail

GM-MP1478

RYR2

Q92736

Chemotherapy-Induced Cognitive Impairment

Translational Medicine

Detail

GM-MP1483

SCARB2

Q14108

Cancer

Nature

Detail

GM-T06093

ROCK2

O75116

Asthma

Nature Communications

Detail

GM-T07931

LILRB2

Q8N423

Nonalcoholic Steatohepatitis

Nature Communications

Detail

GM-T13057

PTPN11

Q06124

Sarcoidosis

Translational Medicine

Detail

GM-T13086

NTN1

O95631

Endometrial Cancer

Nature

Detail

GM-T13086

NTN1

O95631

Cancer EMT

Nature

Detail

GM-T13714

NR1H2

P55055

Antitumor Immunity

Cancer Cell

Detail

GM-T28309

TRPML1

Q9GZU1

Uranium-Induced Nephrotoxicity

Nature Communications

Detail

GM-T56057

KDM6B

O15054

Glioblastoma

Nature Cancer

Detail

GM-T56505

CCN1

O00622

Nonalcoholic Steatohepatitis

Translational Medicine

Detail

GM-T61722

PTGDR2

Q9Y5Y4

Neuroinflammation

Science

Detail

GM-T72534

TNIK

Q9UKE5

Obesity

Science Advances

Detail

GM-T82383

AXL

P30530

Obesity

Nature Communications

Detail

GM-T84040

TRPA1

O75762

Vascular Cognitive Impairment

Science Advances

Detail

GM-T89988

CCR2

P41597

Thrombocytopenia Syndrome Virus

Science Advances

Detail

GM-T99704

VSIR

Q9H7M9

Bone Disease

Nature Communications

Detail

GM-T99732

FGF18

O76093

Liver Ischemia- Reperfusion Injury

Nature Communications

Detail

GM-T87024

APP

P05067

Alzheimer's Disease

Science Advances

Detail

 

ZBP1

Q9H171

Heart Failure

Cell

 

 

ARIH1

Q9Y4X5

Drug-Resistant Cancer

Nature Communications

 

 

NFAT5

O94916

Glioblastoma

Nature Communications

 

 

RNF41

Q9H4P4

Chronic Liver Disease

Translational Medicine

 

 

UHRF1

Q96T88

Lung Cancer

Nature Communications

 

 

TRIM11

Q96F44

Tauopathies

Science

 

 

ACOD1

A6NK06

CAR-Macrophages

Nature Communications

 

 

PARP14

Q460N5

Resistant Cancer

Nature Communications

 

 

PIEZ02

Q9H5I5

Sexual Dysfunction

Science

 

 

Snhg9

RNA

Obesity

Science

 

 

DARS1- AS1

RNA

Glioblastoma

Science Advances

 

 

MAVI1

peptide

Viral Infection

Science

 

 

MEG3

RNA

Alzheimer's Disease

Science

 

TarMart™ is GeneMedi's all-in-one industry solution for therapeutic targets and diagnostics biomarkers. It leverages the robust capabilities of the GM-ITD database to provide an expansive portfolio of product solutions, encompassing a diverse array of target classes.




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