TarMart™-Insight: 100 Potential Hot Targets
'TarMart™-Insight: 100 Potential Hot Targets' is a compilation of 100 potential hot targets in the field of biology. These targets may encompass proteins, genes, or cellular structures that are of significance in drug development, therapeutic research, or biotechnological applications. Each target has been carefully selected and analyzed to determine its potential role and value in relevant fields.
The table is continuously updated to ensure it reflects the latest hot targets.
The data from our second edition:
100 Hot Targets Spotlighted | TarMart™-Insight , last refreshed in August 2023.
The data from our third edition:
100 Hot Targets in Focus in 2024 | TarMart™-Insight , last refreshed in March 2024.
| Target ID | Target | Uniprot Accession | Disease | Publication link | Target Detail |
| GM-T27826 | SPTBN1 | Q01082 | NASH; Cancer (Liver cancer) | Science Translational Medicine | Detail |
| GM-T35527 | 12-LOX | P18054 | NASH | Science Translational Medicine | Detail |
| GM-T06800 | SOCS1 | O15524 | Cancer (CAR-T) | Science Immunology | Detail |
| GM-MP0129 | B4GALT1 | P15291 | Cardiovascular disease | Science | Detail |
| GM-SE1026 | IL27 | Q8NEV9 | Obesity | Nature | Detail |
| GM-T47657 | LTK | P29376 | Cancer (Non-small cell lung cancer) | Nature | Detail |
| GM-T77913 | H1R | P35367 | Cancer | Cancer Cell | Detail |
| GM-T29355 | DNMT3A | Q9Y6K1 | Cancer (CAR-T) | Science Translational Medicine | Detail |
| GM-TA058 | MTHFD2 | P13995 | Inflammation; Autoimmune diseases | Immunity | Detail |
| GM-T92078 | DPYSL2 | Q16555 | Pain | Science Translational Medicine | Detail |
| GM-T09185 | DDR1 | Q08345 | Cancer | Nature | Detail |
| GM-T51487 | GABRA1 | P14867 | Cancer | Nature | Detail |
| GM-T56871 | KDM5B | Q9UGL1 | Cancer | Nature | Detail |
| GM-MP0522 | GPR171 | O14626 | Cancer | Nature Communications | Detail |
| GM-T12819 | RFWD2 | Q8NHY2 | Cancer (Triple-negative breast cancer) | Cell | Detail |
| GM-T91130 | LRP-1 | Q07954 | Rift Valley Fever | Cell | Detail |
| GM-IP0190 | TNK1 | Q13470 | Cancer | Nature Communications | Detail |
| GM-T66505 | SMO | Q99835 | Ischemic stroke | Science Translational Medicine | Detail |
| GM-IP2708 | RIOK2 | Q9BVS4 | Cancer (Acute myeloid leukemia) | Blood | Detail |
| GM-T14143 | TGFB2 | P61812 | Fibrotic diseases | Science Translational Medicine | Detail |
| GM-T22978 | TGFB3 | P10600 | Fibrotic diseases | Science Translational Medicine | Detail |
| GM-T02469 | PIP5K3 | Q9Y2I7 | Cancer (Prostate cancer) | Nature Cancer | Detail |
| GM-T53975 | CXCR6 | O00574 | Cancer | Cell | Detail |
| GM-T85857 | TSLP | Q969D9 | Obesity | Science | Detail |
| GM-T49102 | NEK2 | P51955 | Cancer (Pancreatic cancer) | Nature Communications | Detail |
| GM-MP0220 | CD93 | Q9NPY3 | Cancer | Science Translational Medicine | Detail |
| GM-T95878 | RSK6 | Q9UK32 | Cancer (Lung cancer and bladder cancer) | Science Translational Medicine | Detail |
| GM-SE1027 | IL3 | P08700 | Alzheimer's disease | Nature | Detail |
| GM-T56474 | TNFAIP3 | P21580 | Cancer (Lung cancer) | Science Translational Medicine | Detail |
| GM-MP0545 | GPR75 | O95800 | Obesity | Science | Detail |
| GM-MP0874 | NEU1 | Q99519 | Hypertrophic cardiomyopathy | European Heart Journal | Detail |
| GM-MP0648 | JAG1 | P78504 | NASH | Science Translational Medicine | Detail |
| GM-T12241 | CTH | P32929 | Bacterial infections | Science | Detail |
| GM-MP1798 | TIMD4 | Q96H15 | Cancer | Cancer Cell | Detail |
| GM-T56308 | IL11 | P20809 | Liver injury | Science Translational Medicine | Detail |
| GM-T45593 | MAPT | P10636 | Vascular cognitive impairment and dementia (VCID) | Science Translational Medicine | Detail |
| GM-T23000 | GSN | P06396 | Cancer | Cell | Detail |
| GM-SE1408 | H6PD | O95479 | Cancer (Prostate cancer) | Science Translational Medicine | Detail |
| GM-T92185 | PAC1R | P41586 | Alzheimer's disease | Science Translational Medicine | Detail |
| GM-T92628 | BAP1 | Q92560 | Cancer (Leukemia) | Nature Cancer | Detail |
| GM-IP0276 | ABCB10 | Q9NRK6 | Fatty liver | Science Translational Medicine | Detail |
| GM-T44458 | CDK9 | P50750 | Cancer | Cell | Detail |
| GM-T11615 | SLC7A11 | Q9UPY5 | Cancer (Pancreatic cancer) | Cancer Research | Detail |
| GM-T40332 | NE | P08246 | Cancer | Cell | Detail |
| GM-T15068 | FAK | Q05397 | Cancer (Melanoma) | Nature Communications | Detail |
| GM-IP1618 | SETDB1 | Q15047 | Cancer | Nature | Detail |
| GM-T13057 | PTPN11 | Q06124 | Diabetes | Science Translational Medicine | Detail |
| GM-T76846 | MC3R | P41968 | Anorexia nervosa | Science Translational Medicine | Detail |
| GM-MP0143 | BTN1A1 | Q13410 | Cancer | AACR Annual Meeting 2021 | Detail |
| GM-IP1616 | SERPINB13 | Q9UIV8 | Diabetes | Science Translational Medicine | Detail |
| GM-T28887 | HDAC8 | Q9BY41 | Cancer | Science Translational Medicine | Detail |
| GM-T72010 | LCN2 | P80188 | Pancreatic cancer cachexia | Nature Communications | Detail |
| GM-T31479 | PLA2G1B | P04054 | Cancer | Science Translational Medicine | Detail |
| GM-SE1568 | SVEP1 | Q4LDE5 | Atherosclerosis | Science Translational Medicine | Detail |
| GM-MP2122 | FGD5 | Q6ZNL6 | Cancer (Triple-negative breast cancer) | Science Translational Medicine | Detail |
| GM-MP1417 | PSAP | P07602 | Atherosclerosis | Science Translational Medicine | Detail |
| GM-MP0223 | CDCP1 | Q9H5V8 | Cancer (CAR-T; Pancreatic cancer) | Nature Communications | Detail |
| GM-IP2195 | TSPAN8 | P19075 | Cancer (CAR-T; Pancreatic cancer) | Nature Communications | Detail |
| GM-T44513 | CD66c | P40199 | Cancer (CAR-T; Pancreatic cancer) | Nature Communications | Detail |
| GM-TA074 | IL17RB | Q9NRM6 | Cancer (Pancreatic cancer) | Science Translational Medicine | Detail |
| GM-T47081 | PPIA | P62937 | Cancer (Multiple myeloma) | Nature Medicine | Detail |
| GM-MP0710 | KLRB1 | Q12918 | Cancer (Diffuse glioma) | Cell | Detail |
| GM-T95842 | SLC16A1 | P53985 | Cancer | Nature | Detail |
| GM-TA016 | POLR2A | P24928 | Cancer (Breast cancer) | Science Translational Medicine | Detail |
| GM-T17656 | IRE1a | O75460 | Lupus | Journal of Clinical Investigation | Detail |
| GM-MP0313 | CNNM4 | Q6P4Q7 | NASH | Journal of Hepatology | Detail |
| GM-MP2316 | SAMHD1 | Q9Y3Z3 | HIV | Nature Communications | Detail |
| GM-T30035 | STC1 | P52823 | Cancer | Cancer Cell | Detail |
| GM-T85435 | INSR | P06213 | Diabetes | Nature | Detail |
| GM-MP0249 | CEACAM7 | Q14002 | Cancer (Pancreatic cancer; CAR-T) | Clinical Cancer Research | Detail |
| GM-T27889 | ACE2 | Q9BYF1 | Cancer (Renal cell carcinoma) | Science Translational Medicine | Detail |
| GM-T64485 | AGT | P01019 | Cancer (Renal cell carcinoma) | Science Translational Medicine | Detail |
| GM-T58298 | CD39 | P49961 | Cancer | Science Translational Medicine | Detail |
| GM-TA039 | GLS | O94925 | Aging | Science | Detail |
| GM-T12108 | CRY1 | Q16526 | Cancer | Nature Communications | Detail |
| GM-T95736 | MAP3K14 | Q99558 | Cancer | Nature Immunology | Detail |
| ID3 | Q02535 | Cancer (CAR-T) | Cell | ||
| SOX4 | Q06945 | Cancer (CAR-T) | Cell | ||
| CLIP1 | P30622 | Cancer (Non-small cell lung cancer) | Nature | ||
| UBC9 | P63279 | Pain | Science Translational Medicine | ||
| MEF2 | Q02078 | Alzheimer's disease | Science Translational Medicine | ||
| TRAPPC4 | Q9Y296 | Cancer | Nature Communications | ||
| PUS7 | Q96PZ0 | Cancer (Glioblastoma) | Nature Cancer | ||
| DAXX | Q9UER7 | Cancer; Alzheimer's disease | Nature | ||
| ZMYND8 | Q9ULU4 | Cancer (Acute myeloid leukemia) | Molecular Cell | ||
| eIF4A3 | P38919 | Cancer | Science Advances | ||
| SAB | O60239 | NASH | Hepatology | ||
| IGF2BP3 | O00425 | Cancer (Leukemia) | Leukemia | ||
| CHMP7 | Q8WUX9 | Amyotrophic lateral sclerosis (ALS) | Science Translational Medicine | ||
| RBM39 | Q14498 | Cancer | Cell | ||
| SIRT6 | Q8N6T7 | Aging | Nature Communications | ||
| MCAD | P11310 | Cancer (Glioblastoma) | Cancer Discovery | ||
| PP2A | Q15257 | Cancer | Cell | ||
| METTL3 | Q86U44 | Cancer (Leukemia) | Nature | ||
| VPS39 | Q96JC1 | Diabetes | Nature Communications | ||
| ANLN | Q9NQW6 | Cancer (Triple-negative breast cancer) | Nature Communications | ||
| DNPH1 | O43598 | Cancer (Breast cancer, ovarian cancer) | Science | ||
| ALYREF | Q86V81 | Cancer (Neuroblastoma) | Nature Communications | ||
| Fli1 | Q01543 | Cancer; Infection | Cell | ||
| NSD3 | Q9BZ95 | Cancer | Nature | ||
| YTHDF2 | Q9Y5A9 | Cancer (Glioblastoma) | Nature Communications | ||
| KAT7 | O95251 | Aging | Science Translational Medicine | ||
| ZMYND8 | Q9ULU4 | Cancer (Breast cancer) | Cancer Research | ||
| USP47 | Q96K76 | Cancer (Chronic myeloid leukemia) | Nature Communications |
TarMart™ is GeneMedi's all-in-one industry solution for therapeutic targets and diagnostics biomarkers. It leverages the robust capabilities of the GM-ITD database to provide an expansive portfolio of product solutions, encompassing a diverse array of target classes.
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