SHISA4: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of SHISA4. The page also collects GeneMedi's different modalities and formats products for SHISA4 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SHISA4 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID | GM-IP1634 |
| Target Name | SHISA4 |
| Gene ID | 149345,77552,360848,708341,100683706,101100106,617754,100063707 |
| Gene Symbol and Synonyms | 9330132O05Rik,C1orf40,mShisa4,Prmp,RGD1312041,SHISA4,TMEM58 |
| Uniprot Accession | Q96DD7 |
| Uniprot Entry Name | SHSA4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000198892 |
| Target Classification | N/A |
Pre-made anti-SHISA4 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-SHISA4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SHISA4 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-SHISA4 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Cytokine antibody | Detail |
Recombinant multi-species SHSA4/ SHISA4/ C1orf40 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SHISA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| SHISA4 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Cytokine Products for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse shisa family member 4 (SHISA4) His+Avi (Biotinylated) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
SHISA4 (Shisa Family Member 4) is a Protein Coding gene. Diseases associated with SHISA4 include Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome 1. An important paralog of this gene is SHISA2.
| Target | Species | Antigen Product Name | Bioactivity validation of Antigen | Antibody Product Name | Bioactivity validation of Antibodies | Detail |
| SHISA4 | Human, Cynomolgus/Rhesus macaque, rat, mouse | shisa family member 4 (SHISA4) protein | Affintiy&bioactivity validated by ELISA, cell culture validated | Anti-SHISA4 monoclonal antibody | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). | Detail |
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