Anti-TIKI2/ TRABD2B functional antibody
Anti-TIKI2/ TRABD2B functional antibody for cell culture, ELISA & in-vivo assay
Go to TRABD2B/TRABD2B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE1672-Ab-1/ GM-Tg-hg-SE1672-Ab-2 | Anti-Human TRABD2B monoclonal antibody | Human |
GM-Tg-rg-SE1672-Ab-1/ GM-Tg-rg-SE1672-Ab-2 | Anti-Rat TRABD2B monoclonal antibody | Rat |
GM-Tg-mg-SE1672-Ab-1/ GM-Tg-mg-SE1672-Ab-2 | Anti-Mouse TRABD2B monoclonal antibody | Mouse |
GM-Tg-cynog-SE1672-Ab-1/ GM-Tg-cynog-SE1672-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TRABD2B monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE1672-Ab-1/ GM-Tg-felg-SE1672-Ab-2 | Anti-Feline TRABD2B monoclonal antibody | Feline |
GM-Tg-cang-SE1672-Ab-1/ GM-Tg-cang-SE1672-Ab-2 | Anti-Canine TRABD2B monoclonal antibody | Canine |
GM-Tg-bovg-SE1672-Ab-1/ GM-Tg-bovg-SE1672-Ab-2 | Anti-Bovine TRABD2B monoclonal antibody | Bovine |
GM-Tg-equg-SE1672-Ab-1/ GM-Tg-equg-SE1672-Ab-2 | Anti-Equine TRABD2B monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE1672-Ab-1/ GM-Tg-hg-SE1672-Ab-2; GM-Tg-rg-SE1672-Ab-1/ GM-Tg-rg-SE1672-Ab-2; GM-Tg-mg-SE1672-Ab-1/ GM-Tg-mg-SE1672-Ab-2; GM-Tg-cynog-SE1672-Ab-1/ GM-Tg-cynog-SE1672-Ab-2; GM-Tg-felg-SE1672-Ab-1/ GM-Tg-felg-SE1672-Ab-2; GM-Tg-cang-SE1672-Ab-1/ GM-Tg-cang-SE1672-Ab-2; GM-Tg-bovg-SE1672-Ab-1/ GM-Tg-bovg-SE1672-Ab-2; GM-Tg-equg-SE1672-Ab-1/ GM-Tg-equg-SE1672-Ab-2 |
Products Name | Anti-TRABD2B monoclonal antibody |
Format | mab |
Target Name | TRABD2B |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-TRABD2B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE1672-Ag-1 | Recombinant multi-species TIKI2/ TRABD2B protein |
ORF Viral Vector | pGMLPm004487 | mouse Trabd2b Lentivirus plasmid |
ORF Viral Vector | vGMLPm004487 | mouse Trabd2b Lentivirus particle |
Target information
Target ID | GM-SE1672 |
Target Name | TRABD2B |
Gene ID | 388630,666048,689914,712301,610174,101098071,787081,100063464 |
Gene Symbol and Synonyms | Gm12824,Hkat,RGD1564942,TIKI2,TRABD2B |
Uniprot Accession | A6NFA1 |
Uniprot Entry Name | TIKI2_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000269113 |
Target Classification | N/A |
The target: TRABD2B, gene name: TRABD2B, also named as TIKI2. Enables Wnt-protein binding activity and metalloendopeptidase activity. Involved in several processes, including negative regulation of Wnt signaling pathway; positive regulation of protein oxidation; and positive regulation of protein-containing complex assembly. Is integral component of organelle membrane and integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.