Anti-ARMC5/ AIMAH2 functional antibody

Anti-ARMC5/ AIMAH2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ARMC5/ARMC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1515-Ab-1/ GM-Tg-hg-SE1515-Ab-2Anti-Human ARMC5 monoclonal antibodyHuman
GM-Tg-rg-SE1515-Ab-1/ GM-Tg-rg-SE1515-Ab-2Anti-Rat ARMC5 monoclonal antibodyRat
GM-Tg-mg-SE1515-Ab-1/ GM-Tg-mg-SE1515-Ab-2Anti-Mouse ARMC5 monoclonal antibodyMouse
GM-Tg-cynog-SE1515-Ab-1/ GM-Tg-cynog-SE1515-Ab-2Anti-Cynomolgus/ Rhesus macaque ARMC5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1515-Ab-1/ GM-Tg-felg-SE1515-Ab-2Anti-Feline ARMC5 monoclonal antibodyFeline
GM-Tg-cang-SE1515-Ab-1/ GM-Tg-cang-SE1515-Ab-2Anti-Canine ARMC5 monoclonal antibodyCanine
GM-Tg-bovg-SE1515-Ab-1/ GM-Tg-bovg-SE1515-Ab-2Anti-Bovine ARMC5 monoclonal antibodyBovine
GM-Tg-equg-SE1515-Ab-1/ GM-Tg-equg-SE1515-Ab-2Anti-Equine ARMC5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1515-Ab-1/ GM-Tg-hg-SE1515-Ab-2; GM-Tg-rg-SE1515-Ab-1/ GM-Tg-rg-SE1515-Ab-2;
GM-Tg-mg-SE1515-Ab-1/ GM-Tg-mg-SE1515-Ab-2; GM-Tg-cynog-SE1515-Ab-1/ GM-Tg-cynog-SE1515-Ab-2;
GM-Tg-felg-SE1515-Ab-1/ GM-Tg-felg-SE1515-Ab-2; GM-Tg-cang-SE1515-Ab-1/ GM-Tg-cang-SE1515-Ab-2;
GM-Tg-bovg-SE1515-Ab-1/ GM-Tg-bovg-SE1515-Ab-2; GM-Tg-equg-SE1515-Ab-1/ GM-Tg-equg-SE1515-Ab-2
Products NameAnti-ARMC5 monoclonal antibody
Formatmab
Target NameARMC5
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ARMC5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1515-Ag-1Recombinant multi-species ARMC5/ AIMAH2 protein


    Target information

    Target IDGM-SE1515
    Target NameARMC5
    Gene ID79798,233912,361653,715103,489931,101081595,515835,100064673
    Gene Symbol and SynonymsAIMAH2,ARMC5
    Uniprot AccessionQ96C12,Q5PQP9
    Uniprot Entry NameARMC5_HUMAN,ARMC5_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000140691
    Target ClassificationN/A

    The target: ARMC5, gene name: ARMC5, also named as AIMAH2. This gene encodes a member of the ARM (armadillo/beta-catenin-like repeat) superfamily. The ARM repeat is a tandemly repeated sequence motif with approximately 40 amino acid long. This repeat is implicated in mediating protein-protein interactions. The encoded protein contains seven ARM repeats. Mutations in this gene are associated with primary bilateral macronodular adrenal hyperplasia, which is also known as ACTH-independent macronodular adrenal hyperplasia 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.