Rat Lcn2/Sip24 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_130741.1)

Product information

Catalog No.	Product Name	Plasmid Grade	Plasmid quantity
pGMAAV000092	Rat Lcn2 Adeno-associate virus(AAV) plasmid	Research Grade	10mg, 50mg, 100mg, 500mg, >1g
		GMP-like Grade	10mg, 50mg, 100mg, 500mg, >1g
		High Quality (HQ) Grade
		Seed	5ug

Product Description

Catalog ID	pGMAAV000092
Gene Name	Lcn2
Accession Number	NM_130741.1
Gene ID	170496
Species	Rat
Product Type	Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length	597 bp
Gene Alias	Sip24
Fluorescent Reporter	EGFP
Mammalian Cell Selection
Fusion Tag	3xflag (C-Terminal)
Promoter	CMV
Resistance	Amplicin

Reference

Data / case study

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Associated products

Category	Cat No.	Products Name
Target Antibody	GM-Tg-g-T72010-Ab	Anti-NGAL/ LCN2/ 24p3 functional antibody
Target Antigen	GM-Tg-g-T72010-Ag	LCN2 protein
ORF Viral Vector	pGMLV001321	Human LCN2 Lentivirus plasmid
ORF Viral Vector	pGMAD001066	Human LCN2 Adenovirus plasmid
ORF Viral Vector	pGMAAV000092	Rat Lcn2 Adeno-associate virus(AAV) plasmid
ORF Viral Vector	pGMPC000637	Human LCN2 Mammalian (Non-Viral Vector) plasmid
ORF Viral Vector	pGMPC000792	Human LCN2 Mammalian (Non-Viral Vector) plasmid
ORF Viral Vector	pGMLP002859	Human LCN2 Lentivirus plasmid
ORF Viral Vector	vGMLV001321	Human LCN2 Lentivirus particle
ORF Viral Vector	vGMAD001066	Human LCN2 Adenovirus particle
ORF Viral Vector	vGMAAV000092	Rat Lcn2 Adeno-associate virus(AAV) particle
ORF Viral Vector	vGMLP002859	Human LCN2 Lentivirus particle

Target information

Target ID	GM-T72010
Target Name	LCN2
Gene ID	3934, 16819, 697208, 170496, 491320, 526639, 100070310
Gene Symbol and Synonyms	24p3,LCN2,MSFI,NGAL,NRL,p25,Sip24
Uniprot Accession	P80188
Uniprot Entry Name	NGAL_HUMAN
Protein Sub-location	Secreted Protein/Potential Cytokines
Category	Therapeutics Target, Diagnostics Biomarker
Disease	Prostate Cancer, Complications of kidney transplant, Congenital hydronephrosis, Congenital occlusion of ureteropelvic junction, Contact with and (suspected) exposure to hazardous aromatic compounds, Contrast - Induced Nephropathy, Delayed Graft Function, Dent disease, Diabetic Nephropathy, HIV-Associated Nephropathy, Hydronephrosis, Hypertension, Impaired renal function disease, Injury to Kidney, Intraoperative Renal Injury, Kidney transplant rejection, Lupus Glomerulonephritis, Neonatal urinary tract infection, Nephrectomy, Nephropathy induced by other drugs, medicaments and biological substances, Nephrotic syndrome, Nephrotic syndrome with diffuse membranous glomerulonephritis, Proteinuria, Renal fibrosis, Renovascular hypertension, Sepsis due to Enterococcus, Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction, Systemic lupus erythematosus (SLE), Transplanted Heart Complication, Type 1 diabetes mellitus with diabetic nephropathy, Acute pancreatitis, Asphyxia neonatorum, Autosomal Dominant Polycystic Kidney Disease, Cardiogenic shock, Chronic Kidney Disease, Type 2 diabetes mellitus, Vasculitis, Vesicoureteral reflux
Gene Ensembl	ENSG00000148346
Target Classification	Not Available

This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]

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